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Grants to Prevent Prescription Drug/Opioid Overdose-Related Deaths

This funding record is inactive. Please see the program website or contact the program sponsor to determine if this program is currently accepting applications or will open again in the future.

Catalog of Federal Domestic Assistance Number: 93.243
Substance Abuse and Mental Health Services Administration, U.S. Department of Health and Human Services
Mar 1, 2021

For program and eligibility questions:

Michael Amoh

Damaris Richardson

For fiscal and budget questions:
Corey Sullivan
240.276.1213 or 240.276.1412


This program provides funding to states, U.S. territories, and the Red Lake Band of Chippewa that receive the Substance Abuse Prevention and Treatment Block Grant to reduce the number of prescription drug and opioid overdose-related deaths and adverse events among individuals 18 years of age and older.

Required program activities include, but are not limited to:

  • Completion of a needs assessment of the prescription drug and opioid overdose issue to identify areas and populations of greatest need and select communities of high need on which to focus prevention activities
  • Identify entities serving the selected communities of high need, such as substance abuse treatment providers, emergency medical services agencies, agencies and organizations working with prison and jail populations and offender reentry programs, healthcare providers, harm reduction groups, pharmacies, and community health centers
  • Use SAMHSA's Opioid Overdose Prevention Toolkit as a guide to develop and implement a comprehensive prevention program
  • Develop and disseminate a naloxone distribution plan
  • Purchase naloxone for first responders and others in high-need communities, if necessary
  • Pay for expenses incurred from naloxone distribution, including assembling of naloxone kits and other necessary materials
  • Identify and train community-based substance abuse treatment providers, other organizations/agencies, and key community sectors on overdose death prevention strategies
  • Educate and work with individuals who use opioids, their families, and other close associates on the dangers of overdose, recognizing and responding appropriately to overdose, accessing and using naloxone, and accessing substance abuse treatment and recovery support services

Eligibility is limited to state governments, including the District of Columbia, U.S. territories, Pacific jurisdictions, and the Red Lake Band of the Chippewa, that receive the Substance Abuse Prevention and Treatment Block Grant (SABG). The agency in the state that manages the 20% prevention set-aside of the SABG and has completed a comprehensive substance abuse prevention strategic plan is the only entity that may apply.

Geographic coverage
Eligibility is limited to states, U.S. territories, pacific jurisdictions, and tribal entities that receive the Substance Abuse Prevention and Treatment Block grants.
Amount of funding

Estimated award amount: $850,000 per year for up to 5 years
Estimated total funding: $11,397,000
Anticipated Number of Awards: 13

Application process

Links to the full announcement, application instructions, and the online application process are available through

Tagged as
American Indian or Alaska Native · Mortality · Native Hawaiian or Pacific Islander · Prescription drug misuse · Substance use and misuse

For complete information about funding programs, including your application status, please contact funders directly. Summaries are provided for your convenience only. RHIhub does not take part in application processes or monitor application status.