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Research to Improve Native American Health (R01 and R21)

This funding record is inactive. Please see the program website or contact the program sponsor to determine if this program is currently accepting applications or will open again in the future.

Catalog of Federal Domestic Assistance Number: 93.393
National Cancer Institute, National Institute of Dental and Craniofacial Research, National Institute of Environmental Health Sciences, National Institute of Mental Health, National Institute on Alcohol Abuse and Alcoholism, National Institute on Drug Abuse, National Institute on Minority Health and Health Disparities, National Institutes of Health, Office of Behavioral and Social Sciences Research, U.S. Department of Health and Human Services
Letter of Intent (Optional): Apr 14, 2020
Application: May 14, 2020

Scientific/research, peer review, and financial/grants management contacts by research area are listed in the application instructions.


This opportunity provides grants for research designed to improve Native American health, including:

  • Conducting secondary analysis of existing data
  • Merging various sources of data to answer critical research questions
  • Conducting pilot and feasibility studies
  • Assessing and validating measures that are being developed and/or adapted for use in Native American communities

Studies should:

  1. Be culturally appropriate and result in promoting the adoption of healthy lifestyles
  2. Improve behaviors and social conditions and/or improve environmental conditions related to chronic disease
  3. Prevent or reduce the consumption of tobacco, alcohol, and other drugs
  4. Improve mental health outcomes
  5. Reduce risk of HIV infection
  6. Improve treatment adherence and/or healthcare systems adopting standards of care to improve overall quality of life

There are two funding opportunities under this program:

  1. R21 Exploratory/Developmental Research Grant for the development of new research activities in the early and conceptual stages
  2. R01 Research Project Grant that supports a discrete project to be performed by an investigator in an area representing the investigator's specific interest and competencies

Eligible applicants include:

  • Higher education institutions
    • Public/state controlled institutions
    • Private institutions
  • Nonprofit organizations
    • With 501(c)(3) status
    • Without 501(c)(3) status
    • Native American tribal organizations
    • Faith-based or community-based organizations
    • Regional organizations
  • Governments
    • State
    • County
    • City or township
    • Special districts
    • Federally recognized Indian/Native American tribal governments
    • Indian/Native American tribal governments (other than federally recognized)
    • Eligible agencies of the federal government
    • U.S. territory or possession
  • Other
    • Independent school districts
    • Public housing authorities
    • Indian housing authorities
    • Non-domestic entities and non-domestic components of U.S. entities
    • Small businesses
    • For-profit organizations
Geographic coverage
Nationwide and U.S. territories
Amount of funding

R21: The combined budget for direct costs for the 2 year project period may not exceed $275,000. No more than $200,000 in direct costs may be requested in any single year.

R01: Project budgets are not limited but need to reflect the actual needs of the proposed project. The maximum project period is 5 years.

Application process

Links to the full announcement and online application procedures are available on

While not required, it is suggested that a letter of intent be emailed to Dr. Shobha Srinivasan 30 days prior to the application deadline.

Note that there are several CFDA numbers assigned to this program.

  • 93.113 - Environmental health
  • 93.242 - Mental health research
  • 93.273 - Alcohol research
  • 93.279 - Drug abuse and addiction research
  • 93.307 - Minority health and health disparities research
  • 93.393 - Cancer cause and prevention research
Tagged as
American Indians, Alaska Natives, and Native Hawaiians · Behavioral health · Cultural competency · HIV and AIDS · Research methods and resources · Substance abuse

For complete information about funding programs, including your application status, please contact funders directly. Summaries are provided for your convenience only. RHIhub does not take part in application processes or monitor application status.