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Responding to Opioid Use Disorders in Tribal Communities in the Context of SAMHSA and CDC Funding (R61/R33 - Clinical Trials Optional)

This funding record is inactive. Please see the program website or contact the program sponsor to determine if this program is currently accepting applications or will open again in the future.

Catalog of Federal Domestic Assistance Number: 93.279
National Institute on Drug Abuse, National Institutes of Health, Tribal Health Research Office, U.S. Department of Health and Human Services
Letter of Intent (Optional): Oct 29, 2018
Application: Nov 29, 2018

Scientific/research contacts:

Kathy Etz, PhD
National Institute on Drug Abuse

Sarah Duffy, PhD
National Institute on Drug Abuse

Mike Spittal, PhD
Office of Behavioral and Social Sciences Research

Peer review contact:
Gerald McLaughlin, PhD

Financial and grants management contact:
Pam Fleming


This program provides funding to support culturally relevant research to improve the response to the opioid crisis in tribal communities by using community engaged research approaches to build science around SAMHSA and/or CDC supported programs. The goal is to identify the most effective prevention and/or treatment approaches for opioid use, misuse, and Opioid Use Disorder and related comorbidities in tribal communities, where unique culture, structures for and access to healthcare, and beliefs about treatment all impact health and social outcomes.

A detailed list of potential research topics in the areas of prevention, treatment, and recovery is provided in the application instructions.

SAMHSA and CDC funding that this opportunity intends to leverage are:

Research will take place in 2 phases:

  • R61 Exploratory/Developmental Phase 1: Support for up to 2 years to develop the project including, where relevant, development and pilot testing of study elements such as measurements, the study design, and/or adaption of intervention
  • R33 Phase 2: Funding for up to 4 years to expand to a full test of the research aims. Phase 2 funding is dependent upon successful completion of Phase 1.

Eligible applicants include:

  • Higher education institutions
    • Public/state controlled institutions
    • Private institutions
  • Nonprofit organizations
    • With 501(c)(3) status
    • Without 501(c)(3) status
    • Native American tribal organizations
    • Faith-based or community-based organizations
    • Regional organizations
  • Governments
    • State
    • County
    • City or township
    • Special districts
    • Federally recognized Indian/Native American tribal governments
    • Indian/Native American tribal governments (other than federally recognized)
    • Eligible agencies of the federal government
    • U.S. territory or possession
  • Other
    • Independent school districts
    • Public housing authorities
    • Indian housing authorities
    • Non-domestic entities
    • Small businesses
    • For-profit organizations
Geographic coverage
Amount of funding

Award ceiling: $500,000 per year
Estimated number of awards: 3-4
Estimated total program funding: $3,000,000

The project period is limited to up to 2 years for the R61 phase and up to 4 years for the R33 Phase. Awards cannot exceed a total of 5 years of funding for the combined phases.

Application process

Links to the full announcement and online application process are available through

While not required, potential applicants are encouraged to email a letter of intent to by October 29, 2018.

Tagged as
American Indian or Alaska Native · Culture and cultural competency · Illicit drug use · Prescription drug misuse · Research methods and resources · Substance use and misuse

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