End-of-Life and Palliative Care Approaches to Advanced Signs and Symptoms (R01 and R21 Clinical Trial Optional)
Scientific/research contact:
Karen A. Kehl, Ph.D.
301.594.8010
kehlka@nih.gov
Peer review contact:
Peer review contact information will appear in the
applicant's eRA Commons account approximately 2 weeks
after the submission date.
Financial and grants management
contact:
Ron Wertz
301.594.2807
wertzr@mail.nih.gov
This program provides funding for research to examine the multi-dimensional foundations, experiences, and management of complex, advanced signs and symptoms at the end of life. Projects that include under-studied populations including NIH-designated health disparity, socioeconomically disadvantaged, rural and/or remote, and sexual and gender minority populations with advanced, serious illness at the end of life are specifically encouraged.
Research projects of interest include, but are not limited to:
- The mechanisms of complex advanced signs and symptoms at the end-of-life that may be modified to improve the symptom experience of the individual or family
- The complex variables affecting the symptom experience including physiological, social, cultural, and emotional variables and confounding variables such as other symptoms and underlying disease
- How type, intensity, complexity, and changes in trajectory of advanced symptoms impact individual and family goals for care
- Develop, test and evaluate efficient, effective strategies for management of complex, advanced signs and symptoms at the end-of-life, including non-pharmacological interventions and current medications
- The impact of advanced signs and symptoms on the seriously ill person and/or the family caregiver
- Explore and describe the roles of the ill person and the family caregiver in identifying, assessing and communicating with clinicians about advanced signs and symptoms
There are two funding opportunities under this program:
- R21 Exploratory/Developmental Research Grant for the development of new research activities in the early and conceptual stages
- R01 Research Project Grant that supports a discrete project to be performed by an investigator in an area representing the investigator's specific interest and competencies
Eligible applicants include:
- Higher education institutions
- Public/state controlled institutions
- Private institutions
- Nonprofit organizations
- With 501(c)(3) status
- Without 501(c)(3) status
- Native American tribal organizations
- Faith-based or community-based organizations
- Regional organizations
- Governments
- State
- County
- City or township
- Special districts
- Federally recognized Indian/Native American tribal governments
- Indian/Native American tribal governments (other than federally recognized)
- Eligible agencies of the federal government
- U.S. territory or possession
- Other
- Independent school districts
- Public housing authorities
- Indian housing authorities
- Non-domestic entities and non-domestic components of U.S. entities
- Small businesses
- For-profit organizations
R21: The combined budget for direct costs for the 2 year project period may not exceed $275,000. No more than $200,000 in direct costs may be requested in any single year.
R01: Project budgets are not limited but need to reflect the actual needs of the proposed project. The maximum project period is 5 years.
Links to the full announcement and online application procedures are available on grants.gov.
Submission dates for all non-AIDS applications may be found on the Standard Due Dates web page. Be aware that there are different standard deadlines for new R21 and R01 projects.
Submission dates for all AIDS and AIDS-related applications may be found on the Standard AIDS Due Dates web page.
This opportunity expires on January 8, 2022.
For complete information about funding programs, including your
application status, please contact funders directly. Summaries are provided
for your convenience only. RHIhub does not take part in application processes
or monitor application status.