CMS: Global Benchmark for Efficient Drug Pricing (GLOBE) Model

Federal Register

Dec 23, 2025

Notice from the Centers for Medicare & Medicaid Services (CMS) seeking comments on a proposed rule implementing the Global Benchmark for Efficient Drug Pricing Model ("GLOBE Model"), a new Medicare payment model under section 1115A of the Social Security Act. The GLOBE Model would test whether a payment model that uses an alternative method for calculating Part B inflation rebate amounts for certain separately payable Part B drugs and biological products reduces costs for Medicare fee-for service (FFS) beneficiaries and the Medicare program while preserving quality of care. Comments are due by February 23, 2026.

Medicare · Pharmacy and prescription drugs · Policy · Reimbursement and payment models