Public Inspection: CMS: Global Benchmark for Efficient Drug Pricing Model

Federal Register

Oct 1, 2026

Pre-publication notice of final rule from the Centers for Medicare & Medicaid Services (CMS) implementing the Global Benchmark for Efficient Drug Pricing Model (GLOBE Model), a new Medicare payment model under section 1115A of the Social Security Act. The GLOBE Model would test whether a payment model that uses an alternative method for calculating Part B inflation rebate amounts for certain separately payable Part B drugs and biological products reduces costs for Original Medicare fee-for-service (FFS) beneficiaries and the Medicare program while preserving quality of care. This rule also summarizes and responds to comments received on the December 23, 2025, proposed rule, including the potential impact of this model on small rural hospitals. These regulations are effective November 30, 2026.

Healthcare facilities · Legislation and regulations · Medicare · Pharmacy and prescription drugs · Reimbursement and payment models