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Rural Health Information Hub

Comprehensive Opioid, Stimulant, and Substance Use Site-Based Program

Catalog of Federal Domestic Assistance Number: 16.838
Bureau of Justice Assistance, U.S. Department of Justice
Jul 1, 2024

Office of Justice Programs Response Center:


The Comprehensive Opioid, Stimulant, and Substance Use Site-Based Program (Short Title: COSSUP) provides grants to develop, implement, and/or expand comprehensive programs in response to the overdose crisis and the impact of illicit opioids, stimulants, or other substances. The program provides resources to support state, local, tribal, and territorial efforts to reduce substance misuse and overdose deaths, increase access to prevention, harm reduction, treatment, and recovery services, and enhance public safety while supporting victims.

Rural and tribal applicants should apply under Subcategory 1c for projects in rural areas, small counties, and tribal areas with a population of fewer than 100,000 or a federally recognized tribe.

Funds may be used for:

  • Identifiable and accessible prescription drug take-back programs for unused controlled substances found in the home and used by hospitals and long-term care facilities
  • Law enforcement and other first responder deflection and diversion programs
  • Education and prevention programs to connect law enforcement agencies with K-12 students
  • Comprehensive, real-time, regional information collection, analysis, and dissemination
  • Naloxone for law enforcement and other first responders
  • Substance use education and prevention programs to connect law enforcement agencies with K-12 students
  • Pre-booking or post-booking treatment alternative-to-incarceration programs, such as pretrial, prosecutor, and court diversion or intervention programs, that serve individuals at high risk for overdose or SUD
  • Court programming to prioritize and expedite treatment and recovery services to individuals at high risk for overdose
  • Evidence-based treatment, harm reduction activities, and recovery support services that are well coordinated between in-custody and community-based providers
  • Transitional or recovery housing and peer recovery support services
  • Embedding social workers, peers, and persons with lived experience to help people navigate the justice system and connect them to treatment and recovery services
  • Field-initiated projects that bring together justice, behavioral health, and public health to implement new or promising practices

Priority will be given to applications that:

  • Advance equity and remove barriers to accessing services and opportunities for communities that have been historically underserved, marginalized, adversely affected by inequality, and disproportionately impacted by crime, violence, and victimization
  • Demonstrate a greater than 50% annual increase in recent drug-related overdose deaths
  • Include a research partner for Category 1 applications

Eligible applicants are city, township, county, and federally recognized tribal governments.

To be eligible under the rural subcategory, a jurisdiction must be defined as rural by HRSA's Rural Health Grants Eligibility Analyzer or be a tribal government.

Geographic coverage
Nationwide and U.S. territories
Amount of funding

Award ceiling: $1,000,000 in the rural/tribal subcategory
Project period: 3 years
Estimated number of awards: 24 rural/tribal awards
Estimated total program funding: $127,300,000

Application process

Links to the full announcement, application instructions, and the online application process are available through

Applicants should submit an SF-424 and an SF-LLL in by July 1, 2024.

Submit the full application, including attachments, in the JustGrants grants management system by July 8, 2024.

Applicant webinar recording

Tagged as
Access · Behavioral health · Criminal justice system · Emergency medical services · Families · Housing and homelessness · Illicit drug use · Networking and collaboration · Prescription drug misuse · Public health · Schools

Organizations (1)

For complete information about funding programs, including your application status, please contact funders directly. Summaries are provided for your convenience only. RHIhub does not take part in application processes or monitor application status.