Strategic Prevention Framework - Partnerships for Success for Communities and Tribes

For program and eligibility questions:

202.924.0334
CSAP.DPP@SAMHSA.hhs.gov

For financial and budget questions:
Office of Financial Resources
240.276.1400
NOFOBudget.CSAP@samhsa.hhs.gov

For review process and application status questions:
Angela Houde
240.276.1091
Angela.Houde@samhsa.hhs.gov

Grants.gov contact center:
800.518.4726
support@grants.gov
Self-service knowledge base

System for award management (SAM):
866.606.8220
Federal service desk

The Strategic Prevention Framework - Partnerships for Success program (Short Title: SPF-PFS-Communities/Tribes) provides funding to build prevention capacity throughout communities and tribes and to strengthen the capacity of local community prevention providers. The purpose of this program is to:

• Help prevent and reduce the initiation and progression of substance use and its related problems by supporting the development and delivery of community-based substance use prevention services that strengthen protective factors, reduce risk factors, build resilience, and promote well-being
• Expand and strengthen the capacity of prevention providers serving communities and tribes to implement evidence-based and evidence-informed prevention strategies

With this funding, SAMHSA aims to strengthen community-level prevention capacity to identify and address local substance use prevention concerns, such as underage drinking and use of cannabis, tobacco, vaping, opioids, methamphetamine, and other emerging substances of concern, as well as the progression of substance use among youth, young adults, and adults. Applicants will be expected to use the Strategic Prevention Framework to address up to 3 substance use disorder prevention priorities identified through a data-driven approach.

Detailed lists of required and allowable activities are provided in the application instructions.

Eligible applicants are domestic public and private, nonprofit entities, including:

• Community- and faith-based organizations
• Federally recognized tribes
• Tribal organizations
• Local governments
• Health facilities or programs operated by or in accordance with a contract or grant with the Indian Health Service

Award ceiling: up to $250,000 per year for communities/tribes serving a population of less than 250,000
Project period: up to 5 years
Estimated number of awards: 13-32
Estimated total program funding: $8,000,000

Links to the full announcement, application instructions, and the online application process are available through grants.gov.

Applicant webinar
(Registration required)
June 25, 2026
2:00 p.m. Eastern