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Strategic Prevention Framework - Partnerships for Success

Catalog of Federal Domestic Assistance Number: 93.243
Substance Abuse and Mental Health Services Administration, U.S. Department of Health and Human Services
Feb 21, 2025

For program and eligibility questions:

Alexandria Washington

Damaris Richardson

For fiscal/budget questions:
Office of Financial Resources

For review process and application status questions:
Samantha Dock Herbster


The Strategic Prevention Framework - Partnerships for Success program (Short Title: SPF-PFS) provides funding to address one of the nation's top substance abuse prevention priorities in youth and adults. Awardees will identify the priority substance use issues in their community and develop strategies to deliver substance misuse prevention and mental health services. The Strategic Prevention Framework (SPF) gives prevention professionals a comprehensive process for addressing the substance misuse and related behavioral health problems facing their communities.

Projects must identify populations served that are vulnerable to behavioral health disparities and focus on outcomes that reduce disparities in people who have systematically experienced greater obstacles to health based on their:

  • Racial or ethnic group
  • Religion
  • Socioeconomic status
  • Gender
  • Age
  • Mental health
  • Cognitive, sensory, or physical disability
  • Sexual orientation or gender identity
  • Geographic location
  • Other characteristics historically linked to discrimination or exclusion

Eligible applicants are domestic public and private, nonprofit entities, including

  • Community-based organizations
  • Federally recognized tribes
  • Tribal organizations
  • Local governments
  • Institutions of higher education
Geographic coverage
Nationwide and U.S. territories
Amount of funding

Award ceiling: $375,000 per year
Project period: 5 years
Estimated number of awards: 44
Estimated total program funding: $16,500,000

Application process

Links to the full announcement, application instructions, and the online application process are available through

Tagged as
Access · Alcohol use · American Indian or Alaska Native · Behavioral health · Children and youth · Health disparities · Illicit drug use · LGBTQ+ · Minorities · Networking and collaboration · People with disabilities · Planning and strategy methods and resources · Poverty · Prescription drug misuse · Substance use and misuse · Tobacco use

Organizations (2)

  • U.S. Department of Health and Human Services, view details
  • Substance Abuse and Mental Health Services Administration, view details

For complete information about funding programs, including your application status, please contact funders directly. Summaries are provided for your convenience only. RHIhub does not take part in application processes or monitor application status.