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Rural Health Information Hub

Patient-Centered Outcomes Research Institute (PCORI) Funding: Broad Pragmatic Studies

This funding record is inactive. Please see the program website or contact the program sponsor to determine if this program is currently accepting applications or will open again in the future.

Patient-Centered Outcomes Research Institute
Letter of Intent (Required): Feb 8, 2022
Application: May 3, 2022

Programmatic questions:
Online inquiry form

Administrative, financial, or technical questions:


This program provides funding to support investigator-initiated proposals for patient-centered comparative clinical effectiveness research projects designed to inform patients, caregivers, clinicians, and other healthcare stakeholders in making personalized clinical decisions across a wide range of conditions, populations, and treatments. Projects must align with one of the following four priority areas:

  • Addressing disparities
  • Assessment of prevention, diagnosis, and treatment options
  • Communication and dissemination of research
  • Improving healthcare systems

Special areas of emphasis for this funding cycle include:

  • Addressing racism, discrimination, and bias in healthcare systems and care delivery
  • Health system–level interventions to improve healthcare worker well-being and reduce burnout.

Priority health disparity target populations include:

  • Racial and ethnic minority groups
  • Low-income groups
  • Residents of rural areas
  • Individuals with special healthcare needs
  • Individuals with disabilities
  • Patients with low health literacy, low numeracy, or limited English proficiency
  • Sexual and gender minority individuals

Eligible applicants include any public or private-sector research organization, including:

  • Nonprofit organizations
  • For-profit organizations
  • Universities and colleges
  • Hospitals and healthcare systems
  • Laboratories and manufacturers
  • Units of local, state, and federal government
Geographic coverage
Amount of funding

Category 1 awards up to $5,000,000 and Category 2 awards between $5,000,000 - $10,000,000.

Project period: Up to 5 years

Application process

Links to additional guidance, application instructions, and the online application portal are available on the program website.

Applicants must submit a letter of intent through the online system by February 8, 2022. Selected applicants will be invited to submit a full application, with a deadline of May 3, 2022.

Tagged as
Access · American Indian or Alaska Native · Behavioral health · Black or African American · Health disparities · Health workforce · Infectious diseases · Maternal health and prenatal care · People with disabilities · Research methods and resources · Social determinants of health · Women

Organizations (1)

  • Patient-Centered Outcomes Research Institute, view details

For complete information about funding programs, including your application status, please contact funders directly. Summaries are provided for your convenience only. RHIhub does not take part in application processes or monitor application status.