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Patient-Centered Outcomes Research Institute (PCORI) Funding: Broad Pragmatic Studies

This funding record is inactive. Please see the program website or contact the program sponsor to determine if this program is currently accepting applications or will open again in the future.

Patient-Centered Outcomes Research Institute
Letter of Intent (Required): Jun 4, 2024
Application: Sep 4, 2024

Programmatic questions:

Administrative, financial, or technical questions:



This program provides funding to support investigator-initiated proposals for patient-centered comparative clinical effectiveness research projects designed to inform patients, caregivers, clinicians, and other healthcare stakeholders in making personalized clinical decisions across a wide range of conditions, populations, and treatments.

Projects must align with at least one of the PCORI National Priorities for Health. Applications may focus on up to three of PCORI's topic themes.

Special research areas of interest for this funding cycle include studies focused on long COVID, social needs/determinants of health, and post-traumatic stress disorder (PTSD).

Funding available under category 3 supports studies that leverage PCORnet® to advance PCORI's national priorities.

Populations of interest include:

  • Underserved racial and ethnic groups
  • Low-income groups
  • Women
  • Children (ages 0 to 17 years)
  • Older adults (ages 65 years and older)
  • Residents of rural areas
  • Individuals with special healthcare needs, including individuals with disabilities
  • Individuals with multiple chronic diseases
  • Individuals with rare diseases
  • Individuals whose genetic makeup affects their medical outcomes
  • Patients with low health literacy or numeracy or limited English proficiency
  • Gender and sexual minorities
  • Veterans and members of the U.S. Armed Forces and their families

Eligible applicants include academic research, private sector research, or study-conducting entities. This may include agencies and instrumentalities of the federal government, nonprofit/for-profit research organizations, and colleges/universities, among others.

Geographic coverage
Amount of funding

Funding amounts:

  • Category 1 awards up to $5,000,000
  • Category 2 awards between $5,000,000 - $10,000,000
  • Category 3 awards up to $10,000,000 for studies that leverage PCORnet® to advance PCORI's national priorities

Project period: Up to 5 years

Application process

Links to additional guidance, application instructions, and the online application portal are available on the program website.

Applicants must submit a letter of intent through the online system by June 4, 2024. Selected applicants will be invited to submit a full application, with a deadline of September 4, 2024.

Applicant webinar
(Registration required)
May 17, 2024
11:30 a.m. - 1:00 p.m. Eastern

Tagged as
Abuse and violence · Access · Aging and aging-related services · American Indian or Alaska Native · Behavioral health · Black or African American · COVID-19 · Cardiovascular disease · Children and youth · Elderly population · Health disparities · Health workforce · Maternal health and prenatal care · Mental health · People with disabilities · Population health · Research methods and resources · Social determinants of health · Substance use and misuse · Trauma-informed care · Women

Organizations (1)

  • Patient-Centered Outcomes Research Institute, view details

For complete information about funding programs, including your application status, please contact funders directly. Summaries are provided for your convenience only. RHIhub does not take part in application processes or monitor application status.