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Health Care Models for Persons with Multiple Chronic Conditions from Populations that Experience Health Disparities: Advancing Health Care towards Health Equity (R01 - Clinical Trials Optional)

Catalog of Federal Domestic Assistance Number: 93.307
National Institute on Minority Health and Health Disparities, National Institutes of Health, U.S. Department of Health and Human Services
Sep 7, 2024

Scientific and grants management contacts by research area are listed in the application instructions.


This opportunity provides funding for research to study the effective adaptation, integration, and implementation of recommended guidelines of care of persons with multiple chronic conditions (MCCs) from populations that experience health disparities.

Specific areas of interest include:

  • Multi-component, multi-level studies in existing or newly proposed healthcare models that explore the integration of guidelines of care, and its impact on attaining optimal health outcomes and increasing health equity based on:
    • Patient characteristics such as age, sex/gender, race and ethnicity, socioeconomic status, sexual orientation and gender identity, geographic location, pregnancy status, state of progression of coexisting chronic diseases, insurance health status and coverage and other measures of the social determinants of health, unique health risk or protective factors
    • Healthcare setting characteristics such as urban or rural location, resources, personnel, U.S. region (states or territories)
  • Studies that compare the effect of different healthcare models or interventions within their components on health outcomes and quality of care or quality improvement
  • Studies that evaluate clinician decision-making and/or healthcare system strategies on prioritizing or integrating guidelines of care
  • Studies that explore the intercommunication among clinicians around recommended guidelines of care and clinical decision-making, and test and evaluate approaches that synergize communication and reduce contradictory recommendations
  • Research on strategies to integrate guidelines of care and enhance care coordination for patients at greater risk for non-adherence or adverse events, including persons with cognitive impairment, and/or complex illnesses and health regimens, and/or challenging housing or work-related conditions
  • Studies that test and evaluate hybrid health care models [for example, combination of health care setting and a non-health care setting, or group-based models of care
  • Studies that test and evaluate interventions that promote proactive health care delivery and how this enhances patient self-management, agency and ability to express opinions; timely continuity of care and referral to needed specialty care and avoidance of unnecessary consultations or emergency room visits; patient/caregiver-clinician shared decision making; care coordination; and/or shared patient care in healthcare settings with limited resources and clinical personnel. The role of health information technology, including telehealth, in proactive health care delivery is of interest.
  • Studies that identify and evaluate the impact of contextual factors outside of the clinical/health care settings on the effectiveness of healthcare model
  • Studies that evaluate the impact of differences or changes in individual healthcare insurance coverage on access to and affordability of needed pharmacotherapy and self-monitoring devices and supplies, utilization of and quality of healthcare services, timely evaluation by subspecialists, and other services
  • Research that tests and evaluates healthcare coordination between traditional and alternative settings and its impact on utilization of and quality of healthcare services, and/or health outcomes
  • Health economic sub-analyses

Eligible applicants include:

  • Higher education institutions
    • Public/state controlled institutions
    • Private institutions
  • Nonprofit organizations
    • With 501(c)(3) status
    • Without 501(c)(3) status
    • Native American tribal organizations
    • Faith-based or community-based organizations
    • Regional organizations
  • Governments
    • State
    • County
    • City or township
    • Special districts
    • Federally recognized Indian/Native American tribal governments
    • Indian/Native American tribal governments (other than federally recognized)
    • U.S. territory or possession
  • Other
    • Independent school districts
    • Public housing authorities
    • Indian housing authorities
    • Small businesses
    • For-profit organizations
Geographic coverage
Nationwide and U.S. Territories
Amount of funding

Application budgets are not limited but need to reflect the actual needs of the proposed project. The maximum project period is 5 years.

Application process

Links to the full announcement and online application process are available through

While not required, potential applicants are encouraged to email a letter of intent to Yewande Oladeinde, PhD at least 30 days prior to the application deadline.

Note: There are multiple CFDA numbers, based on the type of research.

This opportunity expires on September 8, 2024.

Tagged as
Health conditions · Health disparities · Healthcare quality · LGBTQI+ · Racial and ethnic groups · Research methods and resources · Social determinants of health · Uninsured and underinsured

Organizations (3)

For complete information about funding programs, including your application status, please contact funders directly. Summaries are provided for your convenience only. RHIhub does not take part in application processes or monitor application status.