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Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain

This funding record is inactive. Please see the program website or contact the program sponsor to determine if this program is currently accepting applications or will open again in the future.

National Center for Advancing Translational Sciences, National Institute on Drug Abuse, National Institutes of Health
Letter of Intent (Optional): Sep 1, 2023
Application: Nov 1, 2023

Kathy Etz


The N CREW Program will provide funding for community-led research to enhance culturally grounded, strengths-based, effective, and sustainable interventions addressing overdose, substance use, mental health, and pain in Native communities.

Program goals include:

  • Support community prioritized research projects, including research elevating and integrating indigenous knowledge and culture
  • Enhance capacity to conduct locally prioritized research, accomplished through the development and provision of novel, accessible, culturally grounded technical assistance and training, resources, and tools
  • Improve access to and the quality of data on substance use, pain, and related health and wellbeing factors to maximize their potential for use in local decision-making

Examples of projects, activities, and deliverables are provided in the application instructions.


Eligible applicants include:

  • Nonprofit organizations with and without 501(c)(3) status
  • For-profit organizations and small businesses
  • Tribal district governments
  • American Indian/Alaska Native tribal governments (federally recognized and other than federally recognized)
  • Businesses that provide fiscal management services for tribes and Native American serving organizations
Geographic coverage
Amount of funding

Award ceiling: $550,000
Award floor: $200,000
Estimated number of awards: 23

Application process

A link to the application instructions is available on the program website.

While not required, applicants are encouraged to email a letter of intent to by September 1, 2023. Submit an online application through NIH eRA Commons ASSIST by November 1, 2023.

Tagged as
American Indian or Alaska Native · Culture and cultural competency · Illicit drug use · Mortality · Planning and strategy methods and resources · Prescription drug misuse · Research methods and resources · Substance use and misuse

Organizations (2)

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