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Testing Oral Nicotine Pouches Versus Nicotine Replacement Therapy for Cigarette Harm Reduction in Appalachia: The ARISE Study Protocol

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Description
Study protocol for the Appalachian Research to Impact Smoking's Effects (ARISE) study, which will examine how the provision of oral nicotine pouches versus nicotine replacement therapy among adult smokers living in rural Appalachian counties across 11 states.
Author(s)
Amy Wermert, Theodore M. Brasky, Alison M. Newton, et al.
Citation
PLOS ONE, 20(12), e0338503
Date
12/2025
Tagged as
Appalachia · Service delivery models · Tobacco use · Wellness, health promotion, and disease prevention