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Rural Health
Resources by Topic: Prescription drug misuse

Opioid Stewardship Programs in Rural Arizona
Provides an overview of Opioid Stewardship Programs (OSPs), and discusses OSP implementation and knowledge in Arizona from a survey of 39 Arizona rural hospital leaders and professionals. Includes an infographic on the results of the OSP survey and links to OSP training resources.
Author(s): Bridget S. Murphy
Date: 04/2025
Sponsoring organization: Arizona Center for Rural Health
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Controlled Substance Prescribing Patterns Among Fatal Overdose Decedents with an Opioid, Stimulant, or Both Contributing to Death — Pennsylvania, 2017–2022
Reports on deaths involving opioids without stimulants, deaths involving stimulants without opioids, and deaths involving both opioids and stimulants in Pennsylvania between 2017 and 2022. Includes data for rural and urban areas. Discusses the role of opioid prescribing on overdose deaths.
Author(s): Stephanie Hayden, Stanley M. Murzynski, Ashley Bolton, Carrie Thomas Goetz
Citation: MMWR (Morbidity and Mortality Weekly Report), 74(12), 205-209
Date: 04/2025
Sponsoring organization: Centers for Disease Control and Prevention
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The Rural and Urban Supply of Clinicians With a DEA Waiver to Prescribe Buprenorphine in 2022 Prior to the Elimination of the Waiver Requirement
Report explores the differences in rates of clinicians with DEA waivers to prescribe buprenorphine in 2022 in rural versus urban counties. Highlights the rural gaps in access to buprenorphine to treat opioid use disorder prior to the elimination of the DEA waiver requirement in 2023. Provides rural, urban, and regional comparisons.
Date: 04/2025
Sponsoring organization: WWAMI Rural Health Research Center
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Delivering Medications for Opioid Use Disorder in Primary Care: Environmental Scan
Report provides a literature review and interviews with key informants to outline the opioid use disorder (OUD) treatment environment and make policy recommendations. Discusses how changes to regulations have affected access to medications for opioid use disorder (MOUD), how the opioid use environment has changed, and what models and evidence-based tools exist to facilitate OUD treatment, among other issues.
Author(s): Collette Sosnowy, Danielle Durant, Garrett Moran, et al.
Date: 03/2025
Sponsoring organization: Agency for Healthcare Research and Quality
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Epidemiology of 911 Calls for Opioid Overdose in Nogales, Arizona
Presents a study reviewing the 911 calls pertaining to opioid overdose in the Nogales, AZ area. Details the prehospital care received in the rural, borderland community and evaluates EMS's adherence to naloxone distribution protocol.
Author(s): Melody Glenn, Darien Stratton, Keith Primeau, Amber Rice
Citation: Western Journal of Emergency Medicine: Integrating Emergency Care with Population Health, 26(3)
Date: 03/2025
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Drug Overdose Deaths: South Carolina, 2023
Reports drug overdose deaths for South Carolina in 2023 using state vital statistics data. Includes statistics on the demographics of drug-related mortality, unintentional and intentional deaths, drug categories, and selected drugs. Includes county-by-county tables and maps showing totals, rates, and change over time.
Date: 03/2025
Sponsoring organization: South Carolina Department of Public Health
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Comparative Effectiveness of Buprenorphine Adherence with Telemedicine Versus In-Person for Rural and Urban Patients
Compares adherence to buprenorphine for opioid use disorder in telemedicine versus in-person healthcare in rural and urban populations. Utilizes 2017–2022 data from 511 adults and compares 3,302 in-person and 519 telemedicine visits, with breakdowns according to patient characteristics, adherence, gaps in treatment, and rural versus urban location. Discusses changing legislative requirements related to buprenorphine treatment and the potential impact on rural populations.
Author(s): Thomas J. Reese, Nana Addo Padi-Adjirackor, Kevin N. Griffith, et al.
Citation: Journal of the American Pharmacists Association, 65(2), 102318
Date: 03/2025
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Synthetic Opioid and Stimulant Co-Involved Overdose Deaths by Occupation and Industry — United States, 2022
Examines occupations and industries with higher percentages of psychostimulant involvement in synthetic opioid overdose deaths. Includes information on occupations such as mining and farming, fishing, and forestry that are more common in rural areas.
Author(s): Eric W. Lundstrom, Alexandria Macmadu, Andrea L. Steege, Matthew Groenewold
Citation: MMWR (Morbidity and Mortality Weekly Report), 74(10), 173–178
Date: 03/2025
Sponsoring organization: Centers for Disease Control and Prevention
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Mechanisms of Resilience and Coping to Intersectional HIV Prevention and Drug-Use Stigma among People who Inject Drugs in Rural Appalachian Ohio
Analyzes perspectives on resilience and coping strategies and behaviors related to stigma reduction and HIV prevention among people who inject drugs (PWID) in rural Appalachian Ohio, utilizing interview data of 35 PWID. Discusses the role of supports for PWID in improving public health outcomes in rural areas.
Author(s): Stacy Endres-Dighe, Ana D. Sucaldito, Renee McDowell, et al.
Citation: Harm Reduction Journal, 22, 18
Date: 02/2025
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Social Network Barriers to Extended-Release Naltrexone Within Rural Appalachia: Perspectives from Justice-Involved Clients and Clinicians
Presents a study on the role of family, friends, and clinicians can play in influencing naltrexone treatment uptake of people with opioid use disorder (POUD) who are incarcerated in Appalachia. Bases findings on interviews with clinicians and breaks down data by sociodemographic characteristics, substance use, and social network composition, among other measures.
Author(s): Amanda M. Bunting, Carrie B. Oser, Marisa Booty, et al.
Citation: Substance Use & Misuse, 60(5), 758-765
Date: 01/2025
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