Skip to main content
Rural Health Information Hub

Rural Health
Resources by Topic: Research methods and resources

The Obesity-Related Chronic Disease Index (ORCDi), a Novel Composite Metric to Quantify ORCD Burden: An Ecological Study Across U.S. Census Tracts
Analyzes obesity-related conditions across U.S. census-tracts to develop and validate the obesity-related chronic disease index (ORCDi), a metric used to quantify obesity burden at the community level. Utilizes Centers for Disease Control and Prevention (CDC) PLACES 2024 data to analyze health conditions across social vulnerability indices (SVIs) and rural-urban commuting area (RUCA) codes. Discusses the utility of ORCDi as a measure in health research to analyze ORCD burden in various communities.
Author(s): Md Roungu Ahmmad, Fazlay Faruque, Xiaoli Zhang
Citation: The Lancet Regional Health – Americas, 61, 101547
Date: 09/2026
view details
Understanding Cancer Clinical Trial Participation in Rural Communities: A Qualitative Focus Group Study
Analyzes perceptions of cancer clinical trial participation among 30 rural cancer survivors, patients, caregivers, and advocates in rural Florida via focus group interviews. Discusses barriers to clinical trial participation, misunderstandings of clinical trial purpose, process, and accessibility, and other factors associated with rural access, communication, and trust for clinical trials.
Author(s): Yetunde Tagurum, Jennifer N. Wells, Vickie Cater, et al.
Citation: Psycho-Oncology, 35(8), e70572
Date: 08/2026
view details
Rural–Urban Comparisons of Area-Based Socioeconomic Disadvantage and Vulnerability Indices
Analyzes how area-based socioeconomic disadvantage indices vary in their index items and predictive accuracy, including the Neighborhood Atlas Area Deprivation Index (NA-ADI), Standardized Area Deprivation Index, Reproducible Area Deprivation Index, Social Vulnerability Index (SVI), and Neighborhood Disadvantage Index. Compares NA-ADI and SVI discordance and discusses implications for health disparities research.
Author(s): Hannah Lang, Kimberly A. Rollings
Citation: Health Affairs Scholar, 4(7), qxag173
Date: 07/2026
view details
Recruiting Rural Patients for Clinical Research: Lessons From a Colorectal Cancer Screening Trial
Examines the effectiveness of the Colonoscopy Outreach for Rural Communities (CORC) trial in recruiting rural patients via its remotely-delivered patient navigation program. Analyzes location of primary care organizations (PCOs) participating in CORC and their success in recruiting rural patients in clinical research.
Author(s): Gina A. Keppel, Brooke Ike, C. Holly A. Andrilla, Allison M. Cole
Citation: Journal of Rural Health, 42(3), e70189
Date: 07/2026
view details
Rural Hospital Financial Performance: Tools for Data-Driven Decision Making
Webinar recording featuring speakers from the Office of the Assistant Secretary for Planning and Evaluation (ASPE) and the North Carolina Rural Health Research Center discussing two data-driven tools, the Rural Hospital Financial Performance Dashboard and the Hospital Financial Distress Index, that can provide valuable insights into the financial health of rural hospitals.
Additional links: Audio Recording, Webinar Slides
Date: 07/2026
Sponsoring organization: Rural Health Information Hub
view details
A Multiregional Decentralized Clinical Trial Program to Improve Access
Assesses geographic and demographic trends in clinical trial participation at Mayo Clinic during the implementation of a decentralized clinical trials (DCT) program between January 2024 and March 2025.
Author(s): Tufia C. Haddad, Lydia A. Mercado, Jennifer G. Le-Rademacher, et al.
Citation: JAMA Network Open, 9(6), e2617204
Date: 06/2026
view details
Evaluating Underrepresentation in Cancer Clinical Trial Enrollment Across Three National Cancer Institute–Designated Cancer Centers: A Retrospective Demographic Study
Analyzes how the enrollment in cancer clinical trials varies demographically and geographically across three Comprehensive Cancer Centers (Vanderbilt-Ingram Cancer Center, Mays Cancer Center at UT Health San Antonio, Yale Cancer Center). Provides data on rural enrollment by center.
Author(s): Guannan Gong, Jessica Liu, Mahanaz Syed, et al.
Citation: JCO Oncology Advances, 3(2), e2500159
Date: 06/2026
view details
Validity of Area-Based Social Risk Indices Used at Higher-Level Geographies and Clinic Locations
Assesses the suitability of the Reproducible Area Deprivation Index (ReADI, Social Deprivation Index (SDI), and Social Vulnerability Index (SVI) for correctly representing patient risk and health outcomes at 5 geographic levels for both patient and clinic addresses. Discusses the usefulness of the social risk indices for researchers lacking small area location data.
Author(s): Nathaniel Hendrix, Nicole Gladish, Neil S. Kamdar, David H. Rehkopf
Citation: JAMA Network Open, 9(6)
Date: 06/2026
view details
Reporting of Rurality, Deprivation, and Socioeconomic Characteristics in Cancer Clinical Trials A Systematic Review
Examines the frequency in which geographic, socioeconomic, and demographic characteristics are reported in oncology clinical trial publications. Analyzes 441 randomized clinical trial primary reports for reporting of core demographic characteristics, education, insurance status, deprivation index, income, and rurality. Discusses the importance of cancer research that features sociodemographic and geographic breakdowns of data.
Author(s): Joseph M. Unger
Citation: JAMA Network Open, 9(6), e2619836
Date: 06/2026
view details
Effective and Cost-Effective Strategies for Recruiting Rural Adults into a Civic Engagement and Health Behavior Change Research Study
Discusses the underrepresentation of rural populations in health research and strategies to improve their participation. Focuses on a community-based health intervention that took place in Texas and New York and includes data showing the cost effectiveness and impact of rural recruitment strategies.
Author(s): Rebecca A. Seguin-Fowler, Meredith L. Graham, Karla L. Hanson, et al.
Citation: BMC Public Health, 26, 2179
Date: 05/2026
view details