Rural Health
Resources by Topic: Research methods and resources
Study Team Perspectives on a Multisite Randomized Clinical Trial with Underserved Rural Populations: A Mixed Methods Feasibility Analysis
Surveys clinical trial study staff on barriers and facilitators of conducting the iAmHealthy Intervention, a mobile health-based clinical trial focused on addressing obesity among rural families and children. Discusses participant recruitment, engagement, and retention, best practices for communicating study procedures and expectations, experiences working with rural populations, and more.
Author(s): Kristina L. Foster, Sarah Sanders, Christi A. Madden, et al.
Citation: PLoS One, 20(9), e0333229
Date: 09/2025
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Surveys clinical trial study staff on barriers and facilitators of conducting the iAmHealthy Intervention, a mobile health-based clinical trial focused on addressing obesity among rural families and children. Discusses participant recruitment, engagement, and retention, best practices for communicating study procedures and expectations, experiences working with rural populations, and more.
Author(s): Kristina L. Foster, Sarah Sanders, Christi A. Madden, et al.
Citation: PLoS One, 20(9), e0333229
Date: 09/2025
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Primary Care Practice-Based Research Networks and Publications, 2014– 2023: Synthesis Report: Identifying and Supporting the Needs of Primary Care Practice-Based Research Networks
Describes the research and publication work of Practice-Based Research Networks between 2014 and 2023. Discusses topic areas addressed more and less frequently as well as challenges for PBRNs that are smaller, less established, and not associated with an academic facility. Discusses recommendations for future research to close knowledge gaps including for rural research.
Author(s): Asta Sorensen, Amelia Kelly, Peter DiMilia, et al.
Date: 09/2025
Sponsoring organizations: Agency for Healthcare Research and Quality, National Center for Excellence in Primary Care Research
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Describes the research and publication work of Practice-Based Research Networks between 2014 and 2023. Discusses topic areas addressed more and less frequently as well as challenges for PBRNs that are smaller, less established, and not associated with an academic facility. Discusses recommendations for future research to close knowledge gaps including for rural research.
Author(s): Asta Sorensen, Amelia Kelly, Peter DiMilia, et al.
Date: 09/2025
Sponsoring organizations: Agency for Healthcare Research and Quality, National Center for Excellence in Primary Care Research
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A Review of Common Limitations in Rural Related Studies in the Peer-Reviewed Literature
Examines rural-focused research studies and their data limitations, such as quality of data, generalizability, numerous rural definitions, outdated data, and more. Reviews 259 research studies published between 2019-2022 in prominent peer-reviewed journals to analyze study characteristics and author-reported limitations.
Author(s): Stephanie M. Mathis, Olivia A. Sullivan, Margaret M. Francisco, et al.
Date: 09/2025
Sponsoring organization: ETSU/NORC Rural Health Research Center
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Examines rural-focused research studies and their data limitations, such as quality of data, generalizability, numerous rural definitions, outdated data, and more. Reviews 259 research studies published between 2019-2022 in prominent peer-reviewed journals to analyze study characteristics and author-reported limitations.
Author(s): Stephanie M. Mathis, Olivia A. Sullivan, Margaret M. Francisco, et al.
Date: 09/2025
Sponsoring organization: ETSU/NORC Rural Health Research Center
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The National Dementia Workforce Study: The Plan for Organization Sample Frames and Data Collection
Details a plan for sampling and recruitment procedures of the dementia workforce, focusing on previously unsampled populations working in assisted living communities or home health agencies. Discusses sampling and recruitment strategies with considerations for Census region and rural areas.
Author(s): James Wagner, Laura M. Wagner, Sheryl Zimmerman, et al.
Citation: Journal of the American Geriatrics Society
Date: 09/2025
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Details a plan for sampling and recruitment procedures of the dementia workforce, focusing on previously unsampled populations working in assisted living communities or home health agencies. Discusses sampling and recruitment strategies with considerations for Census region and rural areas.
Author(s): James Wagner, Laura M. Wagner, Sheryl Zimmerman, et al.
Citation: Journal of the American Geriatrics Society
Date: 09/2025
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Conducting Research That Matters to Rural Practice and Communities
Commentary describing activities designed to improve rural clinical and community engagement in research led by the Oregon Rural Practice Research Network and the WWAMI (Washington, Wyoming, Alaska, Montana and Idaho) region Practice and Research Network. Features example solutions for meaningful engagement.
Author(s): Sebastian T. Tong, Melinda M. Davis, Allison M. Cole
Citation: Journal of the American Board of Family Medicine, 38(2), 603-606
Date: 08/2025
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Commentary describing activities designed to improve rural clinical and community engagement in research led by the Oregon Rural Practice Research Network and the WWAMI (Washington, Wyoming, Alaska, Montana and Idaho) region Practice and Research Network. Features example solutions for meaningful engagement.
Author(s): Sebastian T. Tong, Melinda M. Davis, Allison M. Cole
Citation: Journal of the American Board of Family Medicine, 38(2), 603-606
Date: 08/2025
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Six Strategies for Engaging Rural Communities in Teen Pregnancy Prevention Research and Programming
Tip sheet on communication strategies related to teen pregnancy and STI prevention for rural health researchers and practitioners. Highlights the value of humility, flexibility, and reciprocity in health communication and discusses examples and best practices from the Mousehouse Family Health Study sexual health intervention in Georgia.
Author(s): Asari Offiong, André Marria, Alyssa Scott, Elizabeth Cook, Jennifer Manlove
Date: 08/2025
Sponsoring organization: Child Trends
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Tip sheet on communication strategies related to teen pregnancy and STI prevention for rural health researchers and practitioners. Highlights the value of humility, flexibility, and reciprocity in health communication and discusses examples and best practices from the Mousehouse Family Health Study sexual health intervention in Georgia.
Author(s): Asari Offiong, André Marria, Alyssa Scott, Elizabeth Cook, Jennifer Manlove
Date: 08/2025
Sponsoring organization: Child Trends
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The National Dementia Workforce Study: Methods for Surveying Community Clinicians Who Provide Care to People With Dementia
Discusses the design and significance of the National Dementia Workforce Study (NDWS) Community Clinician Survey, which surveys community-based providers of clinical care for people with dementia. Highlights survey methodology related to provider demographics, processes of care, geographic distribution, and more.
Author(s): Elizabeth M. White, James Wagner, Kate Stewart, et al.
Citation: Journal of the American Geriatrics Society
Date: 08/2025
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Discusses the design and significance of the National Dementia Workforce Study (NDWS) Community Clinician Survey, which surveys community-based providers of clinical care for people with dementia. Highlights survey methodology related to provider demographics, processes of care, geographic distribution, and more.
Author(s): Elizabeth M. White, James Wagner, Kate Stewart, et al.
Citation: Journal of the American Geriatrics Society
Date: 08/2025
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COVID-19 Risk Stratification among Older Adults: A Machine Learning Approach to Identify Personal and Health-Related Risk Factors
Examines risk perceptions and health behaviors related to COVID-19 to create a predictive model to classify individuals into risk categories. Analyzes individual features such as demographic variables, health conditions, adherence to public health guidelines, health literacy, and urbanicity.
Author(s): Arezoo Abasi, Seyed Abbas Motevalian, Haleh Ayatollahi
Citation: BMC Public Health 25, 2577
Date: 07/2025
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Examines risk perceptions and health behaviors related to COVID-19 to create a predictive model to classify individuals into risk categories. Analyzes individual features such as demographic variables, health conditions, adherence to public health guidelines, health literacy, and urbanicity.
Author(s): Arezoo Abasi, Seyed Abbas Motevalian, Haleh Ayatollahi
Citation: BMC Public Health 25, 2577
Date: 07/2025
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Evaluating the Effectiveness of a Mobile HIV Prevention App to Increase HIV and Sexually Transmitted Infection Testing and Pre-Exposure Prophylaxis Initiation Among Rural Men Who Have Sex With Men in the Southern United States: Protocol for a Randomized Controlled Trial
Describes a study protocol that plans to analyze the effectiveness of using a mobile app to increase HIV and sexually transmitted infection (STI) testing and pre-exposure prophylaxis (PrEP) initiation among men who have sex with men (MSM) in the rural South. Discusses recruitment and analysis methods in this type 2 hybrid effectiveness-implementation randomized controlled trial.
Author(s): Jeb Jones, Georgia Manley, Tiffany R Glynn, et al.
Citation: JMIR Research Protocols, 14
Date: 07/2025
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Describes a study protocol that plans to analyze the effectiveness of using a mobile app to increase HIV and sexually transmitted infection (STI) testing and pre-exposure prophylaxis (PrEP) initiation among men who have sex with men (MSM) in the rural South. Discusses recruitment and analysis methods in this type 2 hybrid effectiveness-implementation randomized controlled trial.
Author(s): Jeb Jones, Georgia Manley, Tiffany R Glynn, et al.
Citation: JMIR Research Protocols, 14
Date: 07/2025
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Machine Learning to Evaluate the Effects of Non-Clinical Social Determinant Features in Predicting Colorectal Cancer Mortality in a Medically Underserved Appalachian Population
Examines colorectal cancer (CRC) survival rates in rural Appalachia and the related impact of demographic, clinical, and social determinant of health (SDOH) factors. Utilizes machine learning (ML) models to analyze data from Appalachian cancer centers and examines what factors contribute most to CRC survival in Appalachia. Discusses the impact of including SDOH in ML prediction models and implications for further CRC research.
Author(s): Aisha Montgomery, Ravi Vadapalli, Frank A. Dinenno, et al.
Citation: Scientific Reports, 15, 25781
Date: 07/2025
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Examines colorectal cancer (CRC) survival rates in rural Appalachia and the related impact of demographic, clinical, and social determinant of health (SDOH) factors. Utilizes machine learning (ML) models to analyze data from Appalachian cancer centers and examines what factors contribute most to CRC survival in Appalachia. Discusses the impact of including SDOH in ML prediction models and implications for further CRC research.
Author(s): Aisha Montgomery, Ravi Vadapalli, Frank A. Dinenno, et al.
Citation: Scientific Reports, 15, 25781
Date: 07/2025
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