Iowa Models and Innovations
These stories feature model programs and successful rural projects that can serve as a source of ideas. Some of the projects or programs may no longer be active. Read about the criteria and evidence-base for programs included.
Evidence-Based Examples
PROSPER Partnerships
Updated/reviewed June 2025
- Need: An approach to support sustained, quality delivery of evidence-based programs for youth and families in rural communities.
- Intervention: PROSPER, a program delivery system, guides communities in implementing evidence-based programs that build youth competencies, improve family functioning, and prevent risky behaviors, particularly substance use.
- Results: Youth in PROSPER communities reported delayed initiation of a variety of substances, lower levels of other behavioral problems, and improvements in family functioning and other life skills.
Effective Examples
Parent Partners
Updated/reviewed April 2025
- Need: To support parents whose children have been removed from the home so that the parents can make the changes needed for the children to return safely home.
- Intervention: A statewide program in Iowa pairs these parents with mentors who have successfully navigated their own child welfare cases.
- Results: Participants' children were more likely to return home than non-participants' children, and participants were less likely to have another child removal within a year of the child coming home.
Promising Examples
The Rural Virtual Infusion Program
Updated/reviewed November 2025
- Need: Allow rural cancer patients in a region inclusive of 26 counties in Iowa, Minnesota, and South Dakota to have access to tertiary-level chemotherapy regimens administered in rural infusion centers.
- Intervention: With telehealth-based oversight from a tertiary care oncology team, 3 rural infusion teams were trained to coordinate cancer treatment plans and administer complex chemotherapy regimens.
- Results: The original grant-supported effort — with its results of saving 130 patients 65,000 trip miles and 1,800 travel hours – proved sustainable.
TelePrEP
Updated/reviewed May 2025
- Need: To prevent new cases of HIV in rural Iowa.
- Intervention: TelePrEP provides preventive care via telehealth and prescription delivery.
- Results: Between February 2017 and August 2020, TelePrEP received 456 referrals, with 403 patients completing an initial visit.
Other Project Examples
Promise Community Health Center Hypertension Control Program
Added February 2026
- Need: To improve hypertension in rural Iowa patients.
- Intervention: Promise Community Health Center offers team-based care to help patients manage hypertension.
- Results: The center increased its hypertension control rate from 73% in 2022 to 84% in 2024.
Last Reviewed: 2/12/2026

