Cancer Prevention and Treatment in Rural Areas – Resources
Selected recent or important resources focusing on Cancer Prevention and Treatment in Rural Areas.
Machine Learning to Evaluate the Effects of Non-Clinical Social Determinant Features in Predicting Colorectal Cancer Mortality in a Medically Underserved Appalachian Population
Examines colorectal cancer (CRC) survival rates in rural Appalachia and the related impact of demographic, clinical, and social determinant of health (SDOH) factors. Utilizes machine learning (ML) models to analyze data from Appalachian cancer centers and examines what factors contribute most to CRC survival in Appalachia. Discusses the impact of including SDOH in ML prediction models and implications for further CRC research.
Author(s): Aisha Montgomery, Ravi Vadapalli, Frank A. Dinenno, et al.
Citation: Scientific Reports, 15, 25781
Date: 07/2025
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Examines colorectal cancer (CRC) survival rates in rural Appalachia and the related impact of demographic, clinical, and social determinant of health (SDOH) factors. Utilizes machine learning (ML) models to analyze data from Appalachian cancer centers and examines what factors contribute most to CRC survival in Appalachia. Discusses the impact of including SDOH in ML prediction models and implications for further CRC research.
Author(s): Aisha Montgomery, Ravi Vadapalli, Frank A. Dinenno, et al.
Citation: Scientific Reports, 15, 25781
Date: 07/2025
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Cancer in Rural America: Improving Access to Clinical Trials and Quality of Oncologic Care
Discusses the importance of rural populations accessing oncologic clinical trials to decrease cancer morbidity and mortality rates in rural areas. Provides rural versus urban patient data on distance from trial sites as well as prevalence of chronic disease. Suggests strategies and policies to improve access to clinical trials.
Author(s): Joseph M. Unger, Barbara L. McAneny, Raymond U. Osarogiagbon
Citation: CA: A Cancer Journal for Clinicians, 75(4), 341-361
Date: 07/2025
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Discusses the importance of rural populations accessing oncologic clinical trials to decrease cancer morbidity and mortality rates in rural areas. Provides rural versus urban patient data on distance from trial sites as well as prevalence of chronic disease. Suggests strategies and policies to improve access to clinical trials.
Author(s): Joseph M. Unger, Barbara L. McAneny, Raymond U. Osarogiagbon
Citation: CA: A Cancer Journal for Clinicians, 75(4), 341-361
Date: 07/2025
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Implementing a Tribally Engaged Lung Cancer Screening Pilot Program in Rural Oklahoma
Presents a study on the efficacy of a lung cancer screening program within a tribally operated health system in the Choctaw Nation of Oklahoma. Bases findings on pre- and post-intervention surveys. Makes recommendation for program expansion and highlights key barriers and facilitators to implementation.
Author(s): Zsolt Nagykaldi, Mark Doescher, Dorothy A. Rhoades, et al.
Citation: Cancer Prevention Research, 18(7), 423-430
Date: 07/2025
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Presents a study on the efficacy of a lung cancer screening program within a tribally operated health system in the Choctaw Nation of Oklahoma. Bases findings on pre- and post-intervention surveys. Makes recommendation for program expansion and highlights key barriers and facilitators to implementation.
Author(s): Zsolt Nagykaldi, Mark Doescher, Dorothy A. Rhoades, et al.
Citation: Cancer Prevention Research, 18(7), 423-430
Date: 07/2025
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Difference-Making Factors for Successful Implementation of a Multicomponent Colorectal Cancer Screening Program in Rural Clinics (SMARTER CRC)
Evaluates multicomponent colorectal cancer screening programs at 14 rural primary care clinics to identify factors associated with higher rates of screening. Interventions include using mailed outreach materials and patient navigation programs in partnership with health plans. Discusses the effectiveness of outreach activities conducted by the clinic or a third-party vendor as well as collaborations between clinics and health plans.
Author(s): Amanda F. Petrik, Brittany Badicke, Melinda M. Davis, et al.
Citation: Frontiers in Medicine, 12
Date: 06/2025
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Evaluates multicomponent colorectal cancer screening programs at 14 rural primary care clinics to identify factors associated with higher rates of screening. Interventions include using mailed outreach materials and patient navigation programs in partnership with health plans. Discusses the effectiveness of outreach activities conducted by the clinic or a third-party vendor as well as collaborations between clinics and health plans.
Author(s): Amanda F. Petrik, Brittany Badicke, Melinda M. Davis, et al.
Citation: Frontiers in Medicine, 12
Date: 06/2025
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Interventions to Increase Colorectal Cancer Screening Uptake in Rural Settings: A Scoping Review
Scoping review examining 36 studies on interventions to increase colorectal cancer (CRC) screening uptake in rural communities. Highlights approaches and strategies of effective interventions and discusses the need for continued research on tailored interventions for underserved communities.
Author(s): Christine M. Kava, Judith Lee Smith, Emily K. Kobernik, et al.
Citation: Preventing Chronic Disease, 22, 250025
Date: 06/2025
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Scoping review examining 36 studies on interventions to increase colorectal cancer (CRC) screening uptake in rural communities. Highlights approaches and strategies of effective interventions and discusses the need for continued research on tailored interventions for underserved communities.
Author(s): Christine M. Kava, Judith Lee Smith, Emily K. Kobernik, et al.
Citation: Preventing Chronic Disease, 22, 250025
Date: 06/2025
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Logistic and Time Burdens Reported by Gynecologic and Breast Cancer Survivors
Examines logistic and time burdens of cancer care in breast and gynecologic cancer survivors. Analyzes survey feedback from 224 participants related to travel time, wait time, and trips to the cancer center, with data breakdowns according to patient's employment, education, cancer type and treatment status, dependent status, income, and rural versus urban residence. Discusses the impact of cancer care on time for other activities.
Author(s): Allison C. Dona, Aisha Ambo, Patricia Jewett, et al.
Citation: BMC Women's Health, 25, 273
Date: 06/2025
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Examines logistic and time burdens of cancer care in breast and gynecologic cancer survivors. Analyzes survey feedback from 224 participants related to travel time, wait time, and trips to the cancer center, with data breakdowns according to patient's employment, education, cancer type and treatment status, dependent status, income, and rural versus urban residence. Discusses the impact of cancer care on time for other activities.
Author(s): Allison C. Dona, Aisha Ambo, Patricia Jewett, et al.
Citation: BMC Women's Health, 25, 273
Date: 06/2025
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Risks of Adverse Health Outcomes among Older Rural Prostate Cancer Survivors in the SEER-Medicare Data
Analyzes health outcomes and disparities in prostate cancer survivors living in rural areas. Compares 37,126 rural and 109,176 urban prostate cancer survivors over the age of 66 to provide data breakdowns according to sociodemographics, health status and behaviors, cancer characteristics, type of treatment, adverse health outcomes, and risk of death.
Author(s): Chun-Pin Chang (Esther), Daren Huang, Shane Lloyd, et al.
Citation: Journal of Rural Health, 41(2)
Date: 05/2025
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Analyzes health outcomes and disparities in prostate cancer survivors living in rural areas. Compares 37,126 rural and 109,176 urban prostate cancer survivors over the age of 66 to provide data breakdowns according to sociodemographics, health status and behaviors, cancer characteristics, type of treatment, adverse health outcomes, and risk of death.
Author(s): Chun-Pin Chang (Esther), Daren Huang, Shane Lloyd, et al.
Citation: Journal of Rural Health, 41(2)
Date: 05/2025
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National Survey of Lung Cancer Screening Eligibility in United States Veterans
Explores a study evaluating the portion of veterans eligible and screened for lung cancer in rural and urban areas. Discusses the differences in screening and mortality rates between rural and urban areas. Breaks down data by age, family cancer history, and smoking history, among other factors.
Author(s): Jennifer A. Lewis, Allison Stranick, Jacquelyn Pennings, et al.
Citation: American Journal of Preventive Medicine, 68(5), 886-895
Date: 05/2025
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Explores a study evaluating the portion of veterans eligible and screened for lung cancer in rural and urban areas. Discusses the differences in screening and mortality rates between rural and urban areas. Breaks down data by age, family cancer history, and smoking history, among other factors.
Author(s): Jennifer A. Lewis, Allison Stranick, Jacquelyn Pennings, et al.
Citation: American Journal of Preventive Medicine, 68(5), 886-895
Date: 05/2025
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Living With Chronic Myelogenous Leukemia in Rural Communities: Exploring Factors Related to Tyrosine Kinase Inhibitors Adherence With a Mixed Methods Approach
Presents a study on the use of tyrosine kinase inhibitor (TKI), which improves chronic myeloid leukemia (CML) outcomes, among rural CML patients. Bases findings on semi-structured interviews detailing side effects, perceived stress, and ability to self-manage chronic conditions, among other factors.
Author(s): Jingxi Sheng, Sue P. Heiney, Karen E. Wickersham, et al.
Citation: Journal of Rural Health, 41(2), e70028
Date: 04/2025
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Presents a study on the use of tyrosine kinase inhibitor (TKI), which improves chronic myeloid leukemia (CML) outcomes, among rural CML patients. Bases findings on semi-structured interviews detailing side effects, perceived stress, and ability to self-manage chronic conditions, among other factors.
Author(s): Jingxi Sheng, Sue P. Heiney, Karen E. Wickersham, et al.
Citation: Journal of Rural Health, 41(2), e70028
Date: 04/2025
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Social Determinants of Health and Variability in Treatment for Patients with Early-Stage Non-Small Cell Lung Cancer
Examines census tract-level social determinants of health (SDOH) and their impact on lung cancer treatment. Utilizes 2017-2022 Syapse Learning Health Network data to analyze patient social and demographic variables, housing burden, broadband internet access, primary care shortage areas, and rurality, as correlated with radiation therapy and/or surgery.
Author(s): Molly Scannell Bryan, Xiaohan Hu, Monika A. Izano, et al.
Citation: JNCI Cancer Spectrum, 9(2)
Date: 04/2025
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Examines census tract-level social determinants of health (SDOH) and their impact on lung cancer treatment. Utilizes 2017-2022 Syapse Learning Health Network data to analyze patient social and demographic variables, housing burden, broadband internet access, primary care shortage areas, and rurality, as correlated with radiation therapy and/or surgery.
Author(s): Molly Scannell Bryan, Xiaohan Hu, Monika A. Izano, et al.
Citation: JNCI Cancer Spectrum, 9(2)
Date: 04/2025
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Last Updated: 10/2/2025