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Rural Health Information Hub
Rural Health Information Hub

Cancer Prevention and Treatment in Rural Areas – Models and Innovations

These stories feature model programs and successful rural projects that can serve as a source of ideas and provide lessons others have learned. Some of the projects or programs may no longer be active. Read about the criteria and evidence-base for programs included.

Evidence-Based Examples

Updated/reviewed May 2025

  • Need: To enhance palliative care access to rural patients with serious illness, such as advanced cancer, heart failure, and COPD, and their family caregivers.
  • Intervention: Project ENABLE consists of: 1) an initial in-person palliative care consultation with a specialty-trained provider and 2) a semi-structured series of weekly, phone-delivered, nurse-led or palliative care coach/navigator sessions designed to help patients and their caregivers enhance their problem-solving, symptom management, and coping skills.
  • Results: Patients and caregivers report higher quality of life and lower rates of depression and (caregiver) burden.

Updated/reviewed September 2023

  • Need: To help people with chronic conditions learn how to manage their health.
  • Intervention: A small-group 6-week workshop for individuals with chronic conditions to learn skills and strategies to manage their health.
  • Results: Participants have better health and quality of life, including reduction in pain, fatigue, and depression.

Promising Examples

funded by the Federal Office of Rural Health Policy

Updated/reviewed April 2020

  • Need: Allow rural cancer patients in a of 26-county region in Iowa, Minnesota, and South Dakota to have access to tertiary-level chemotherapy regimens in rural infusion centers.
  • Intervention: With telehealth-based oversight from a tertiary care oncology team, 3 rural infusion teams were trained to coordinate cancer treatment plans and administer complex chemotherapy regimens.
  • Results: Almost 130 patients were transitioned to receive chemotherapy in a rural infusion center, translating to over 1,000 infusion visits and saving patients/families nearly 65,000 trip miles, 1,800 travel hours, and $71,000.

Other Project Examples

Added January 2025

  • Need: Rural cancer survivors report lower levels of physical activity and higher rates of psychosocial distress compared to their urban counterparts.
  • Intervention: Researchers collaborated with a rural-serving organization in northeast Texas to test a 3-month intervention which enhanced an existing exercise program with behavioral health education, yoga, and home-based exercise components.
  • Results: Program participants were twice as likely to report meeting physical activity recommendations at post-intervention than participants in a control group and reported significant reductions in psychosocial distress.
funded by the Federal Office of Rural Health Policy

Updated/reviewed March 2020

  • Need: Comprehensive cancer services for residents of an 8-county, 3-state area in Appalachia.
  • Intervention: Using a Cancer Patient Navigation Tool Kit, a Maryland acute care facility led a multidisciplinary collaboration that provided the area's patients with expanded cancer treatment services.
  • Results: In addition to several new cancer-related programs, expanded services are now available for cancer patients, families, and cancer survivors.
Last Reviewed: 7/18/2022