Substance Use and Misuse in Rural Areas – Resources
Selected recent or important resources focusing on Substance Use and Misuse in Rural Areas.
Treatment Initiations and Opioid Overdoses among Recently Incarcerated People after Adoption of the Take-Home Methadone Policy
Explores the effect flexible methadone policies implemented during the COVID-19 pandemic had on opioid overdoses and treatment initiation and uptake among incarcerated people upon release. Highlights the effect this policy had on rural areas and communities that lack access to opioid treatment.
Author(s): Benjamin A. Barsky, Shapei Yan, Meredith B. Rosenthal
Citation: Drug and Alcohol Dependence, 274, 112775
Date: 09/2025
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Explores the effect flexible methadone policies implemented during the COVID-19 pandemic had on opioid overdoses and treatment initiation and uptake among incarcerated people upon release. Highlights the effect this policy had on rural areas and communities that lack access to opioid treatment.
Author(s): Benjamin A. Barsky, Shapei Yan, Meredith B. Rosenthal
Citation: Drug and Alcohol Dependence, 274, 112775
Date: 09/2025
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Pharmacy Barriers to Receiving Buprenorphine Among Patients Undergoing Telemedicine Addiction Treatment
Presents a study exploring pharmacy-level barriers experienced by patients with opioid use disorder who are receiving treatment via telemedicine. Discusses barriers that lead to missed doses or inaccessible prescriptions. Breaks down data by health and demographic characteristics, such as age, education, and insurance type, among others, and whether the patient lived in a rural or nonrural area.
Author(s): Lauren E. Hendy, Lucas G. Hill, Amanda Olguin, et al.
Citation: JAMA Network Open, 8(8), e2527418
Date: 08/2025
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Presents a study exploring pharmacy-level barriers experienced by patients with opioid use disorder who are receiving treatment via telemedicine. Discusses barriers that lead to missed doses or inaccessible prescriptions. Breaks down data by health and demographic characteristics, such as age, education, and insurance type, among others, and whether the patient lived in a rural or nonrural area.
Author(s): Lauren E. Hendy, Lucas G. Hill, Amanda Olguin, et al.
Citation: JAMA Network Open, 8(8), e2527418
Date: 08/2025
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Geographic Disparities by Rural-Urban Status and Drive Time to Care in Tobacco Treatment for COPD
Explores the potential relationship between the drive-time to tobacco dependence treatment (TDT) services and the development of COPD among smokers. Details distances of rural smokers to TDT services. Draws from Veterans Affairs data and breaks down data by demographic characteristics, treatment type, and rural versus urban location, among other measures.
Author(s): Arianne K. Baldomero, Anne C. Melzer, Ken M. Kunisaki, et al.
Citation: JAMA Network Open, 8(8), e2528898
Date: 08/2025
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Explores the potential relationship between the drive-time to tobacco dependence treatment (TDT) services and the development of COPD among smokers. Details distances of rural smokers to TDT services. Draws from Veterans Affairs data and breaks down data by demographic characteristics, treatment type, and rural versus urban location, among other measures.
Author(s): Arianne K. Baldomero, Anne C. Melzer, Ken M. Kunisaki, et al.
Citation: JAMA Network Open, 8(8), e2528898
Date: 08/2025
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Tobacco Product Use or Nicotine Vaping in the Past Month
Report discusses rates of tobacco and nicotine vaping use detailed in the National Survey on Drug Use and Health (NSDUH) from 2022, 2023, and 2024. Features breakdowns by demographics, years and rurality, among other measures.
Date: 08/2025
Sponsoring organization: Substance Abuse and Mental Health Services Administration
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Report discusses rates of tobacco and nicotine vaping use detailed in the National Survey on Drug Use and Health (NSDUH) from 2022, 2023, and 2024. Features breakdowns by demographics, years and rurality, among other measures.
Date: 08/2025
Sponsoring organization: Substance Abuse and Mental Health Services Administration
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Tobacco Retailer Density and Rurality Across Four US States: California, Connecticut, North Carolina, and Ohio
Presents a study on the tobacco retailer density of rural areas. Compares density rates of rural tracts with metropolitan, micropolitan, and small towns. Draws examples from California, Ohio, Connecticut, and North Carolina.
Author(s): Emerson Webb, Peter F. Craigmile, Meghan E. Morean, et al.
Citation: Journal of Rural Health, 41(3), e70073
Date: 08/2025
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Presents a study on the tobacco retailer density of rural areas. Compares density rates of rural tracts with metropolitan, micropolitan, and small towns. Draws examples from California, Ohio, Connecticut, and North Carolina.
Author(s): Emerson Webb, Peter F. Craigmile, Meghan E. Morean, et al.
Citation: Journal of Rural Health, 41(3), e70073
Date: 08/2025
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Prescribed Medications for Patients with Amphetamine-Type Stimulant Use Disorder Seen in Rural-Serving Pacific Northwest Primary Care Clinics
Examines the frequency in which patients living in the rural Pacific Northwest with amphetamine-type stimulant use disorder (AT-StUD) received medications for AT-StUD in primary care clinics. Utilizes 2017-2021 electronic health record (EHR) data to analyze patients who have received prescriptions according to demographics, mental health status, and health behaviors.
Author(s): Megan J. Yerton, Connor J. McCabe, Matthew D. Iles-Shih, Judith I. Tsui, Kevin A. Hallgren
Citation: Addiction Science & Clinical Practice, 20, 67
Date: 08/2025
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Examines the frequency in which patients living in the rural Pacific Northwest with amphetamine-type stimulant use disorder (AT-StUD) received medications for AT-StUD in primary care clinics. Utilizes 2017-2021 electronic health record (EHR) data to analyze patients who have received prescriptions according to demographics, mental health status, and health behaviors.
Author(s): Megan J. Yerton, Connor J. McCabe, Matthew D. Iles-Shih, Judith I. Tsui, Kevin A. Hallgren
Citation: Addiction Science & Clinical Practice, 20, 67
Date: 08/2025
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Risk & Protective Factors for Rural Youth Substance Use: A Report for the Rural Network
Examines youth substance use in rural areas and various risk and protective factors. Utilizes data from Washington State's Rural Network members to analyze substance use and discusses school-based, family-based, and community-based preventive factors.
Author(s): Ellie Jackson
Date: 08/2025
Sponsoring organizations: Rural Network, WWAMI Rural Health Research Center
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Examines youth substance use in rural areas and various risk and protective factors. Utilizes data from Washington State's Rural Network members to analyze substance use and discusses school-based, family-based, and community-based preventive factors.
Author(s): Ellie Jackson
Date: 08/2025
Sponsoring organizations: Rural Network, WWAMI Rural Health Research Center
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NSDUH (National Survey on Drug Use and Health) Detailed Tables - 2024
Explores 2024 survey data on use of prescription and illicit drugs, alcohol, tobacco and nicotine products, trends in substance use disorder (SUD) and mental illness, and access to treatment for youth and adults. Features statistics for a variety of demographic and geographic characteristics, including rural versus urban status.
Date: 08/2025
Sponsoring organization: Substance Abuse and Mental Health Services Administration
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Explores 2024 survey data on use of prescription and illicit drugs, alcohol, tobacco and nicotine products, trends in substance use disorder (SUD) and mental illness, and access to treatment for youth and adults. Features statistics for a variety of demographic and geographic characteristics, including rural versus urban status.
Date: 08/2025
Sponsoring organization: Substance Abuse and Mental Health Services Administration
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Examining Geographic Disparities in Access to No-Cost Naloxone in North Carolina: A Cross-Sectional Survey of Naloxone Distribution Programs
Presents a study exploring the geographic distribution of no-cost naloxone in North Carolina. Bases findings on a survey of naloxone distributors in the state and breaks down data by user demographics and distributor type.
Author(s): Grace Marley, Caroline Shubel, Carolyn T. Thorpe, et al.
Citation: Journal of Rural Health, 41(3), e70069
Date: 08/2025
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Presents a study exploring the geographic distribution of no-cost naloxone in North Carolina. Bases findings on a survey of naloxone distributors in the state and breaks down data by user demographics and distributor type.
Author(s): Grace Marley, Caroline Shubel, Carolyn T. Thorpe, et al.
Citation: Journal of Rural Health, 41(3), e70069
Date: 08/2025
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Illegally Made Fentanyl Use in the United States: 2022 and 2023
Report highlights findings from the 2022 and 2023 National Survey on Drug Use and Health (NSDUH) on the use of illegally made fentanyl across the U.S. Explores co-usage with other drugs, emergency room visits/hospitalizations, and breaks down user characteristics by age, poverty level, and rurality, among other measures.
Citation: NSDUH Data Brief, 2(2)
Date: 07/2025
Sponsoring organizations: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration
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Report highlights findings from the 2022 and 2023 National Survey on Drug Use and Health (NSDUH) on the use of illegally made fentanyl across the U.S. Explores co-usage with other drugs, emergency room visits/hospitalizations, and breaks down user characteristics by age, poverty level, and rurality, among other measures.
Citation: NSDUH Data Brief, 2(2)
Date: 07/2025
Sponsoring organizations: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration
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Additional resources are available related to this guide. See the full list of resources by topic for:
- Alcohol use
- Behavioral health
- Behavioral health workforce
- Illicit drug use
- Prescription drug misuse
- Substance use and misuse
- Tobacco use
Last Updated: 9/15/2025

