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Rural Health
Resources by Topic: Appalachia

Patient, Facility, and Community Determinants of Timely Follow up after Abnormal Screening Mammograms in Appalachia: A Multilevel Analysis
Examines the impact of community, patient, and facility characteristics on mammogram screening access, mammogram recall, and biopsy rates in 5 Appalachian states. Utilizes 2016-2018 Medicare claims data from breast imaging organizations to analyze characteristics of mammogram care, providing sociodemographic breakdowns and metro versus rural comparisons.
Author(s): Roger T. Anderson, Marianne M. Hillemeier, Jennifer A. Harvey, et al.
Citation: Journal of Rural Health, 42(1), e70104
Date: 01/2026
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Testing Oral Nicotine Pouches Versus Nicotine Replacement Therapy for Cigarette Harm Reduction in Appalachia: The ARISE Study Protocol
Study protocol for the Appalachian Research to Impact Smoking's Effects (ARISE) study, which will examine the provision of oral nicotine pouches versus nicotine replacement therapy among adult smokers living in rural Appalachian counties across 11 states.
Author(s): Amy Wermert, Theodore M. Brasky, Alison M. Newton, et al.
Citation: PLOS ONE, 20(12), e0338503
Date: 12/2025
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Appalachian Regional Commission Performance & Accountability Report: Fiscal Year 2025
Provides an overview of the Appalachian Regional Commission's (ARC) projects from 2025 that develop economy, promote education and healthy living, invest in infrastructure, strengthen natural and cultural heritage, and build capacity in the Appalachian region. Includes healthcare-focused discussions about substance use, healthcare grants, healthcare workforce, and more.
Date: 12/2025
Sponsoring organization: Appalachian Regional Commission
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High-Poverty Counties in Appalachia, 1960 and 2019-2023
Maps showing a comparison of high-poverty Appalachian counties in 1960 and 2019-2023.
Date: 10/2025
Sponsoring organization: Appalachian Regional Commission
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"No Rest for Me Tonight": A Social-Ecological Exploration of Insomnia in Rural Appalachian Women
Examines individual, social, and societal factors associated with insomnia among rural, Appalachian women in Kentucky, analyzing and providing excerpts from interviews with 46 women with self-reported insomnia symptoms. Details the high impact of insomnia on women in rural Appalachia and identifies cultural factors influencing insomnia prevalence and treatment.
Author(s): Mairead E. Moloney, Daniela C. Moga, Michael Grandner, Nancy Schoenberg
Citation: Sleep Health, 11(5), 717-723
Date: 10/2025
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A Twenty-Year Review: Revisiting the Drinking Water and Wastewater Infrastructure Funding Needs and Gaps in the Appalachian Region
Provides county, state, and metro versus nonmetro data on water and wastewater infrastructure in the Appalachian region. Discusses funding and collaborative possibilities to improve critical infrastructure in Appalachian communities.
Additional links: Executive Summary
Author(s): Ahmed Rachid El-Khattabi, Christy M. Ihlo, Leigh Anne Krometis, Kara Millonzi
Date: 08/2025
Sponsoring organization: Appalachian Regional Commission
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Bridging Rural Communities: Telehealth Innovations for Appalachia and Beyond
Video series on innovative approaches to telehealth in rural Appalachia, hosted by the Mid-Atlantic Telehealth Center (MATRC) on August 1, 2025. Features speakers on telehealth use in veterans' healthcare, substance use recovery, palliative care, mental health, healthy aging, emergency preparedness and response, cancer screening, and other topics related to healthcare access, quality of care, and healthcare economics. Transcripts are available via video descriptions.
Date: 08/2025
Sponsoring organization: Mid-Atlantic Telehealth Resource Center
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Improving Access to Specialty Care for Rural Children Using Enhanced Hearing Screening and Specialty Telehealth Follow-Up in Rural Kentucky Schools: Protocol for a Hybrid Effectiveness-Implementation Stepped Wedge, Cluster-Randomized Controlled Trial (Appalachian STAR Trial)
A study protocol for the Appalachian Specialty Telemedicine Access for Referrals (STAR) trial which aims to improve access to specialty hearing care for children living in rural Kentucky. Focuses on school hearing screenings of kindergartners and follow-up referrals to specialty care.
Author(s): Tarika Srinivasan, Samantha Kleindienst Robler, Elizabeth Turner, et al.
Citation: JMIR Research Protocols, 14
Date: 08/2025
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Understanding and Predicting Flossing Behavior in a Rural Appalachian Community Using the Multi-Theory Model
Presents a study on the initiation and sustenance of flossing among people in rural Appalachia. Explores the factors that lead to regular daily flossing and makes recommendations for interventions aimed at making similar behavioral changes.
Author(s): Rahib K. Islam, Manoj Sharma, Amanda H. Wilkerson, et al.
Citation: Nature: Scientific Reports, 15, 30741
Date: 08/2025
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Appalachian Diseases of Despair: Final Report
Analyzes the impact of diseases of despair on mortality within Appalachia, focusing on mortality from alcohol, prescription drug, and illegal drug overdose; suicide; and alcoholic liver disease/cirrhosis of the liver. Includes data through 2023, with demographics and breakdowns by subregion, county economic status, and levels of rurality.
Date: 07/2025
Sponsoring organizations: Appalachian Regional Commission, East Tennessee State University Center for Rural Health Research, NORC Walsh Center for Rural Health Analysis
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