Rural Health
Resources by Topic: Infectious diseases
Higher Mortality Following SARS-CoV-2 Infection in Rural Versus Urban Dwellers Persists for Two Years Post-Infection
Compares two-year post-COVID-19 mortality by level of rurality among patients with SARS-CoV-2 infection which occurred between April 2020 and December 2022, utilizing National Clinical Cohort Collaborative COVID-19 Enclave data. Includes data on overall mortality risk, excess mortality, trends in mortality over time, and new onset conditions among urban, urban-adjacent rural, and nonurban-adjacent rural populations.
Author(s): A. Jerrod Anzalone, Michael T. Vest, Makayla E. Schissel, et al.
Citation: Nature Communications, 16, 8933
Date: 10/2025
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Compares two-year post-COVID-19 mortality by level of rurality among patients with SARS-CoV-2 infection which occurred between April 2020 and December 2022, utilizing National Clinical Cohort Collaborative COVID-19 Enclave data. Includes data on overall mortality risk, excess mortality, trends in mortality over time, and new onset conditions among urban, urban-adjacent rural, and nonurban-adjacent rural populations.
Author(s): A. Jerrod Anzalone, Michael T. Vest, Makayla E. Schissel, et al.
Citation: Nature Communications, 16, 8933
Date: 10/2025
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Cost of Implementing Evidence-Based Practices to Reduce Opioid Overdose Fatalities in New York State Communities
Presents a study on the cost of implementing an intervention to deploy opioid education, naloxone distribution, and medication for opioid use disorder (MOUD) during the COVID-19 pandemic in rural and urban locations in New York. Evaluates data from two time periods, or waves, from January 2020 to June 2022 and July 2022 to December 2023.
Author(s): Jazmine M. Li, Dawn Gruss, Timothy Hunt, et al.
Citation: Addiction Science & Clinical Practice, 20, 77
Date: 10/2025
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Presents a study on the cost of implementing an intervention to deploy opioid education, naloxone distribution, and medication for opioid use disorder (MOUD) during the COVID-19 pandemic in rural and urban locations in New York. Evaluates data from two time periods, or waves, from January 2020 to June 2022 and July 2022 to December 2023.
Author(s): Jazmine M. Li, Dawn Gruss, Timothy Hunt, et al.
Citation: Addiction Science & Clinical Practice, 20, 77
Date: 10/2025
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Sources of Health Insurance among Adults with Long COVID: Estimates from the Medical Expenditure Panel Survey
Examines the prevalence of ongoing symptoms after COVID-19 exposure (Long COVID), prevalence of activity-limiting Long COVID, and sources of health insurance among adults reporting Long COVID, utilizing Medical Expenditure Panel Survey Household Component (MEPS-HC) data. See Tables 1 and 2 for a comparison of the prevalence of Long COVID and activity-limiting Long COVID between metropolitan statistical areas (MSAs) and non-MSAs, among other factors.
Author(s): Thomas M. Selden, Zhengyi Fang, Steven C. Hill
Date: 09/2025
Sponsoring organization: Agency for Healthcare Research and Quality
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Examines the prevalence of ongoing symptoms after COVID-19 exposure (Long COVID), prevalence of activity-limiting Long COVID, and sources of health insurance among adults reporting Long COVID, utilizing Medical Expenditure Panel Survey Household Component (MEPS-HC) data. See Tables 1 and 2 for a comparison of the prevalence of Long COVID and activity-limiting Long COVID between metropolitan statistical areas (MSAs) and non-MSAs, among other factors.
Author(s): Thomas M. Selden, Zhengyi Fang, Steven C. Hill
Date: 09/2025
Sponsoring organization: Agency for Healthcare Research and Quality
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Rural Providers' Attitudes Toward Integrating Harm Reduction Strategies and PrEP Prescribing into Rural Primary Care Settings in the US. Southeast and Midwest
Examines the perceptions of providers working in rural primary care settings toward buprenorphine, methadone, comprehensive harm reduction, and PrEP prescriptions. Analyzes 409 providers treating either a person with opioid use disorder or a person with HIV and provides data breakdowns on PrEP prescriptions, medications for opioid use disorder (MOUD), and perceptions toward harm reduction integration.
Author(s): Phillip L. Marotta, Miryam Biaid, Robert Heimer, et al.
Citation: Addiction Science & Clinical Practice, 20, 73
Date: 09/2025
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Examines the perceptions of providers working in rural primary care settings toward buprenorphine, methadone, comprehensive harm reduction, and PrEP prescriptions. Analyzes 409 providers treating either a person with opioid use disorder or a person with HIV and provides data breakdowns on PrEP prescriptions, medications for opioid use disorder (MOUD), and perceptions toward harm reduction integration.
Author(s): Phillip L. Marotta, Miryam Biaid, Robert Heimer, et al.
Citation: Addiction Science & Clinical Practice, 20, 73
Date: 09/2025
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Addressing HPV Vaccination in Southwest GA: The Emory Cancer Prevention and Control Research Network
Discusses the HPV Vaccine Mini-Grant Program, which funded a multi-level human papillomavirus (HPV) vaccination intervention by four county health departments in rural, Southwest Georgia. Highlights strategies used by participating sites and includes data on program outcomes.
Author(s): Cam Escoffery
Date: 09/2025
Sponsoring organization: St. Jude Children's Research Hospital
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Discusses the HPV Vaccine Mini-Grant Program, which funded a multi-level human papillomavirus (HPV) vaccination intervention by four county health departments in rural, Southwest Georgia. Highlights strategies used by participating sites and includes data on program outcomes.
Author(s): Cam Escoffery
Date: 09/2025
Sponsoring organization: St. Jude Children's Research Hospital
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Navigating Hepatitis C Care: Knowledge Gaps and Access Barriers Among Young Women Who Inject Drugs in Rural Appalachia
Presents a study on the barriers to hepatitis C virus (HCV) testing and treatment for young women who inject drugs (YWID) in rural areas. Aims to identify the factors influencing the accessibility of HCV testing and treatment for YWID in rural Appalachian, Ohio. Bases findings on interviews with 30 YWID aged 18-35 and discusses interpersonal and community barriers to care.
Author(s): Cheyenne R. Wagi, Renee McDowell, Anyssa Wright, et al.
Citation: PLOS ONE
Date: 09/2025
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Presents a study on the barriers to hepatitis C virus (HCV) testing and treatment for young women who inject drugs (YWID) in rural areas. Aims to identify the factors influencing the accessibility of HCV testing and treatment for YWID in rural Appalachian, Ohio. Bases findings on interviews with 30 YWID aged 18-35 and discusses interpersonal and community barriers to care.
Author(s): Cheyenne R. Wagi, Renee McDowell, Anyssa Wright, et al.
Citation: PLOS ONE
Date: 09/2025
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Trends in Influenza- and Pneumonia-Related Mortality in Lung Cancer Patients from 1999 to 2022: A Retrospective CDC WONDER Analysis
Examines demographic factors associated with increased influenza- and pneumonia-related mortality in lung cancer patients, utilizing 1999-2022 CDC WONDER data. Includes data and discussion of rural-urban mortality disparities.
Author(s): Kate Woods, Mustafa Beidas, Vikram Murugan, et al.
Citation: Respiratory Research, 26, 267
Date: 09/2025
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Examines demographic factors associated with increased influenza- and pneumonia-related mortality in lung cancer patients, utilizing 1999-2022 CDC WONDER data. Includes data and discussion of rural-urban mortality disparities.
Author(s): Kate Woods, Mustafa Beidas, Vikram Murugan, et al.
Citation: Respiratory Research, 26, 267
Date: 09/2025
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Modeling the Impact of Changing Drug Markets and Structural Determinants on HCV and/or HIV Transmission Among People Who Inject Drugs in the United States: A Rural and Urban Comparison
Details a study exploring the impact of changing patterns of drug use in rural and urban areas are affecting the rates of hepatitis C virus (HCV) and HIV incidence among people who inject drugs (PWID). Compares rates of infection and drug use in San Diego, CA and rural Central and Northern, WI.
Author(s): Natasha K. Martin, Daniela Abramovitz, William H. Eger, et al.
Citation: International Journal of Drug Policy, 143, 104925
Date: 09/2025
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Details a study exploring the impact of changing patterns of drug use in rural and urban areas are affecting the rates of hepatitis C virus (HCV) and HIV incidence among people who inject drugs (PWID). Compares rates of infection and drug use in San Diego, CA and rural Central and Northern, WI.
Author(s): Natasha K. Martin, Daniela Abramovitz, William H. Eger, et al.
Citation: International Journal of Drug Policy, 143, 104925
Date: 09/2025
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Treatment Initiations and Opioid Overdoses among Recently Incarcerated People after Adoption of the Take-Home Methadone Policy
Explores the effect flexible methadone policies implemented during the COVID-19 pandemic had on opioid overdoses and treatment initiation and uptake among incarcerated people upon release. Highlights the effect this policy had on rural areas and communities that lack access to opioid treatment.
Author(s): Benjamin A. Barsky, Shapei Yan, Meredith B. Rosenthal
Citation: Drug and Alcohol Dependence, 274, 112775
Date: 09/2025
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Explores the effect flexible methadone policies implemented during the COVID-19 pandemic had on opioid overdoses and treatment initiation and uptake among incarcerated people upon release. Highlights the effect this policy had on rural areas and communities that lack access to opioid treatment.
Author(s): Benjamin A. Barsky, Shapei Yan, Meredith B. Rosenthal
Citation: Drug and Alcohol Dependence, 274, 112775
Date: 09/2025
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Evaluating the Impact of Altitudinal Variations on COVID-19 Mortality Rates: A Comprehensive Analysis
Examines the effects of high altitude on county-level COVID-19 mortality, fatality rates, and vaccination outcomes, utilizing January 2020-August 2022 New York Times COVID-19 repository and American Community Survey data. Includes data on fatality by level of rurality in the pre- and post-vaccination periods.
Author(s): Emre Karsli, Damla Anbarli Metin, Arda Kocatas, et al.
Citation: BMC Pulmonary Medicine, 25, 413
Date: 08/2025
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Examines the effects of high altitude on county-level COVID-19 mortality, fatality rates, and vaccination outcomes, utilizing January 2020-August 2022 New York Times COVID-19 repository and American Community Survey data. Includes data on fatality by level of rurality in the pre- and post-vaccination periods.
Author(s): Emre Karsli, Damla Anbarli Metin, Arda Kocatas, et al.
Citation: BMC Pulmonary Medicine, 25, 413
Date: 08/2025
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