Substance Use and Misuse in Rural Areas – Funding & Opportunities
For additional funding options, please see RHIhub's Online Library: Funding & Opportunities
Delta States Rural Development Network Program
Inactive
Grants to support the planning, development, and implementation of integrated healthcare networks within the Delta Region that collaborate to achieve efficiencies; expand access to, coordinate, and improve the quality of basic healthcare services and associated health outcomes; and strengthen the rural healthcare system as a whole.
Grants to support the planning, development, and implementation of integrated healthcare networks within the Delta Region that collaborate to achieve efficiencies; expand access to, coordinate, and improve the quality of basic healthcare services and associated health outcomes; and strengthen the rural healthcare system as a whole.
Geographic coverage: The 8 Delta States: Alabama, Arkansas, Illinois, Kentucky, Louisiana, Mississippi, Missouri, and Tennessee
Application Deadline: Aug 12, 2026
Sponsors: Federal Office of Rural Health Policy, Health Resources and Services Administration, U.S. Department of Health and Human Services
Application Deadline: Aug 12, 2026
Sponsors: Federal Office of Rural Health Policy, Health Resources and Services Administration, U.S. Department of Health and Human Services
Regional Partnership Grants
Inactive
Funding to support collaborative regional partnerships between child welfare agencies, substance use treatment agencies, and juvenile or state courts to support programs for families whose children are in or at risk of being placed in an out-of-home placement due to a caregiver's substance use.
Funding to support collaborative regional partnerships between child welfare agencies, substance use treatment agencies, and juvenile or state courts to support programs for families whose children are in or at risk of being placed in an out-of-home placement due to a caregiver's substance use.
Geographic coverage: Nationwide
Application Deadline: Aug 7, 2026
Sponsors: Administration for Children and Families, U.S. Department of Health and Human Services
Application Deadline: Aug 7, 2026
Sponsors: Administration for Children and Families, U.S. Department of Health and Human Services
Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain
Inactive
Funding for community-led research to enhance culturally grounded, strengths-based, effective, and sustainable interventions addressing overdose, substance use, mental health, and pain in Native communities.
Funding for community-led research to enhance culturally grounded, strengths-based, effective, and sustainable interventions addressing overdose, substance use, mental health, and pain in Native communities.
Geographic coverage: Nationwide
Application Deadline: Jul 31, 2026
Sponsors: National Center for Advancing Translational Sciences, National Institute on Drug Abuse, National Institutes of Health
Application Deadline: Jul 31, 2026
Sponsors: National Center for Advancing Translational Sciences, National Institute on Drug Abuse, National Institutes of Health
Emergency Department Alternatives to Opioids
Inactive
Funding to expand the use of non-opioid pain management protocols for patients presenting with pain in emergency care settings. The program supports early identification of opioid use disorder (OUD) and timely intervention and referral to OUD care. Rural Emergency Hospitals are listed as eligible applicants.
Funding to expand the use of non-opioid pain management protocols for patients presenting with pain in emergency care settings. The program supports early identification of opioid use disorder (OUD) and timely intervention and referral to OUD care. Rural Emergency Hospitals are listed as eligible applicants.
Geographic coverage: Nationwide
Application Deadline: Jul 27, 2026
Sponsors: Substance Abuse and Mental Health Services Administration, U.S. Department of Health and Human Services
Application Deadline: Jul 27, 2026
Sponsors: Substance Abuse and Mental Health Services Administration, U.S. Department of Health and Human Services
First Responders - Comprehensive Addiction and Recovery Act Grants (FR-CARA)
Inactive
Funding to train first responders and communities in administering and distributing opioid overdose reversal medications. Funding is set aside for recipients serving rural and tribal communities.
Funding to train first responders and communities in administering and distributing opioid overdose reversal medications. Funding is set aside for recipients serving rural and tribal communities.
Geographic coverage: Nationwide and U.S. territories
Application Deadline: Jul 27, 2026
Sponsors: Substance Abuse and Mental Health Services Administration, U.S. Department of Health and Human Services
Application Deadline: Jul 27, 2026
Sponsors: Substance Abuse and Mental Health Services Administration, U.S. Department of Health and Human Services
Medication-Assisted Treatment - Prescription Drug and Opioid Addiction (MAT-PDOA)
Inactive
Grants to expand and enhance access to medications for opioid use disorder (MOUD); increase access to treatment and recovery for individuals with opioid use disorder (OUD); and decrease illicit opioid use, prescription opioid misuse, and overdose. Working with rural and resource-limited communities is listed as a required activity.
Grants to expand and enhance access to medications for opioid use disorder (MOUD); increase access to treatment and recovery for individuals with opioid use disorder (OUD); and decrease illicit opioid use, prescription opioid misuse, and overdose. Working with rural and resource-limited communities is listed as a required activity.
Geographic coverage: Nationwide and U.S. territories
Application Deadline: Jul 27, 2026
Sponsors: Substance Abuse and Mental Health Services Administration, U.S. Department of Health and Human Services
Application Deadline: Jul 27, 2026
Sponsors: Substance Abuse and Mental Health Services Administration, U.S. Department of Health and Human Services
Rural Communities Opioid Response Program - Technical Assistance (RCORP-TA)
Inactive
Funding for a single entity to connect rural communities with high-quality, comprehensive, and tailored resources and supports to implement and sustain behavioral healthcare, including prevention, treatment, and recovery services, to address the opioid epidemic and related substance use concerns in rural areas.
Funding for a single entity to connect rural communities with high-quality, comprehensive, and tailored resources and supports to implement and sustain behavioral healthcare, including prevention, treatment, and recovery services, to address the opioid epidemic and related substance use concerns in rural areas.
Geographic coverage: Nationwide and U.S. territories
Application Deadline: Jul 27, 2026
Sponsors: Federal Office of Rural Health Policy, Health Resources and Services Administration, U.S. Department of Health and Human Services
Application Deadline: Jul 27, 2026
Sponsors: Federal Office of Rural Health Policy, Health Resources and Services Administration, U.S. Department of Health and Human Services
Building Communities of Recovery
Inactive
Grants to support organizations in mobilizing and connecting community resources to increase access to long-term recovery support for people with substance use disorders (SUD) and co-occurring substance use and mental disorders. Rural populations are a priority.
Grants to support organizations in mobilizing and connecting community resources to increase access to long-term recovery support for people with substance use disorders (SUD) and co-occurring substance use and mental disorders. Rural populations are a priority.
Geographic coverage: Nationwide
Application Deadline: Jul 16, 2026
Sponsors: Substance Abuse and Mental Health Services Administration, U.S. Department of Health and Human Services
Application Deadline: Jul 16, 2026
Sponsors: Substance Abuse and Mental Health Services Administration, U.S. Department of Health and Human Services
Rural Emergency Medical Services Training Grant (R-EMS)
Inactive
Grants to recruit and train emergency medical services personnel in rural areas with a focus on addressing substance use disorders and co-occurring mental health conditions.
Grants to recruit and train emergency medical services personnel in rural areas with a focus on addressing substance use disorders and co-occurring mental health conditions.
Geographic coverage: Nationwide and U.S. territories
Application Deadline: Jul 16, 2026
Sponsors: Substance Abuse and Mental Health Services Administration, U.S. Department of Health and Human Services
Application Deadline: Jul 16, 2026
Sponsors: Substance Abuse and Mental Health Services Administration, U.S. Department of Health and Human Services
Rural Opioid Technical Assistance Regional Centers (ROTA)
Inactive
Funding to implement regional centers of excellence to develop and disseminate training and technical assistance addressing opioid and stimulant misuse affecting rural communities.
Funding to implement regional centers of excellence to develop and disseminate training and technical assistance addressing opioid and stimulant misuse affecting rural communities.
Geographic coverage: Nationwide and U.S. territories
Application Deadline: Jul 16, 2026
Sponsors: Substance Abuse and Mental Health Services Administration, U.S. Department of Health and Human Services
Application Deadline: Jul 16, 2026
Sponsors: Substance Abuse and Mental Health Services Administration, U.S. Department of Health and Human Services

