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Rural Health Information Hub

Rural Health
Funding by Sponsor: U.S. Department of Health and Human Services

Summaries of funding programs are provided by RHIhub for your convenience. Please contact the funder directly for the most complete and current information.

Notice of Special Interest (NOSI): Implementation Science to Advance Maternal Health and Maternal Health Equity for the IMPROVE Initiative
Notice of Special Interest for research to address health disparities associated with pregnancy-related and pregnancy-associated morbidity and mortality. Populations of focus include American Indians, Alaska Natives, Native Hawaiians, other Pacific Islanders, and underserved rural populations, among others.
Geographic coverage: Nationwide and U.S. Territories
Application Deadline: May 8, 2025
Sponsors: National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Mental Health, National Institute on Drug Abuse, National Institute on Minority Health and Health Disparities, U.S. Department of Health and Human Services
Notice of Special Interest (NOSI): Research Using Implementation Science to Support the Delivery of Evidence-Based Practices in Community-Based Mental or General Medical Healthcare Settings
Notice of Special Interest for mental health services and implementation research to support the adoption and sustainability of evidence-based practices in community-based settings that deliver care to people with mental illness. Health disparity populations, including individuals living in rural areas, are a priority.
Geographic coverage: Nationwide and U.S. Territories
Application Deadline: May 8, 2025
Sponsors: National Institute of Mental Health, National Institute on Drug Abuse, National Institutes of Health, U.S. Department of Health and Human Services
Co-infection and Cancer (R01 and R21 Clinical Trial Not Allowed)
Grants for research on the roles of co-infection and cancer to inform prevention and treatment strategies for infection-related cancers. Applicants are encouraged to investigate co-infection and its relation to causes of risk among racially/ethnically diverse populations and those from urban and rural areas who are poor and medically underserved, and populations who may have a disproportionate burden of infection-related cancers.
Geographic coverage: Nationwide and U.S. territories
Application Deadline: Nov 16, 2025
Sponsors: National Cancer Institute, National Institutes of Health, U.S. Department of Health and Human Services
Notice of Special Interest (NOSI): Firearm Injury and Mortality Prevention Research
Notice of Special Interest for research to improve understanding of the determinants of firearm injury; the identification of those at risk of firearm injury; the development, piloting, and testing of innovative interventions to prevent firearm injury and mortality; and the examination of approaches to improve the implementation of existing, evidence-based interventions to prevent firearm injury and mortality.
Geographic coverage: Nationwide and U.S. Territories
Application Deadline: Feb 5, 2026
Sponsors: National Institute of Mental Health, National Institute on Aging, National Institute on Alcohol Abuse and Alcoholism, National Institute on Drug Abuse, National Institute on Minority Health and Health Disparities, National Institutes of Health, U.S. Department of Health and Human Services
Notice of Special Interest (NOSI): Research to Address Vaccine Hesitancy, Uptake, and Implementation among Populations that Experience Health Disparities
Notice of Special Interest for community-engaged research to evaluate strategies to facilitate vaccination uptake in clinical and community contexts and address the barriers to increasing reach, access, and uptake of vaccinations among health disparity populations at high risk and likely to experience vaccine hesitancy.
Geographic coverage: Nationwide and U.S. Territories
Application Deadline: Jun 6, 2026
Sponsors: National Cancer Institute, National Institute on Minority Health and Health Disparities, National Institutes of Health, U.S. Department of Health and Human Services
Notice of Special Interest (NOSI): Research to Address Vaccine Uptake and Implementation among Populations Experiencing Health Disparities
Notice of Special Interest for research on strategies and interventions to increase vaccine uptake and implementation among populations experiencing health disparities.
Geographic coverage: Nationwide and U.S. Territories
Application Deadline: Jun 6, 2026
Sponsors: National Institutes of Health, U.S. Department of Health and Human Services
AHRQ Small Research Projects to Advance the Science of Primary Care (R03)
Funding to support small research projects that advance the role and capacity of primary care to increase the value and quality of care and improve patient outcomes and population health. Rural populations are among the priority populations.
Geographic coverage: Nationwide and U.S. territories
Application Deadline: Mar 19, 2027
Sponsors: Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services
Long-Term Effects of Disasters on Health Care Systems Serving Health Disparity Populations (R01- Clinical Trial Optional)
Grants for research focused on understanding the long-term effects of natural and/or human-made disasters on healthcare systems serving health disparity populations. Health disparity populations include, but are not limited to, American Indians, Alaska Natives, and underserved rural populations.
Geographic coverage: Nationwide and U.S. territories
Application Deadline: May 7, 2027
Sponsors: National Cancer Institute, National Institute on Aging, National Institute on Minority Health and Health Disparities, National Institutes of Health, U.S. Department of Health and Human Services
AHRQ Health Services Research Demonstration and Dissemination Grants (R18)
Supports the dissemination and implementation of research projects related to AHRQ's mission to produce evidence to make healthcare safer, higher quality, more accessible, equitable, and affordable. AHRQ's priorities include an interest in frontier and rural healthcare delivery.
Geographic coverage: Nationwide and U.S. territories
Application Deadline: May 26, 2029
Sponsors: Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services
AHRQ Health Services Research Projects (R01)
Support for specified health services research projects related to AHRQ's mission to produce evidence to make healthcare safer, higher quality, more accessible, equitable, and affordable. AHRQ's priorities include an interest in rural and frontier healthcare delivery.
Geographic coverage: Nationwide and U.S. territories
Application Deadline: Jul 6, 2029
Sponsors: Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services