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Chronic Disease in Rural America – Resources

Selected recent or important resources focusing on Chronic Disease in Rural America.

Rural/Urban Disparities in the Availability of Diabetes Prevention Programs in US Hospitals
Examines access to Diabetes Prevention Programs (DPPs) by geographic and socioeconomic variables. Analyzes DPPs in 3,204 general medical hospitals according to sociodemographic variables such as food environment, insurance rates, income, and more, as well as hospital characteristics, such as ownership type, geographic region, and county location of metro, micro, or noncore.
Author(s): Allyson Hughes, Shyamkumar Sriram, Berkeley Franz, Cory Cronin
Citation: Journal of Primary Care & Community Health, 16
Date: 09/2025
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Fast Facts: Rates of Chronic Conditions Consistently Higher Among Adults in Rural Areas
Compares the prevalence of chronic health conditions and associated risk factors in rural and urban areas, utilizing 2023 Behavioral Risk Factor Surveillance System (BRFSS) data. Includes data on health conditions including obesity, chronic obstructive pulmonary disease, cardiovascular disease, arthritis, diabetes, chronic kidney disease, and depression, among others. Includes state-by-state rural health data for select conditions.
Date: 09/2025
Sponsoring organization: America's Health Rankings
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Examining the Burden of Chronic Disease and Low SES to Identify High-Need Rural Counties
Analyzes the geographic and sociodemographic profile of rural, high-need counties in the United States. Examines chronic disease prevalence, socioeconomic status, and access to healthcare facilities by county, with additional breakdowns by demographic characteristics of low-, moderate-, and high-need counties.
Author(s): Gabriel A. Benavidez, Emma Boswell, Peiyin Hung, Elizabeth Crouch
Citation: Journal of Public Health Management & Practice, 31(5), 691-699
Date: 09/2025
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Disparities in Timely Access to Certified Stroke Care Among US Census Tracts, by Prevalence of Health Risk Factors
Examines census tract-level demographic and health characteristics associated with drive times of greater than 60 minutes from certified stroke care or advanced stroke care in the contiguous United States. Highlights rural access disparities and discusses implications for health practice to improve stroke care access in underserved areas.
Author(s): Linda Schieb, Joshua Tootoo, Melissa Fiffer, et al.
Citation: Preventing Chronic Disease, 22, 240429
Date: 07/2025
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Cancer in Rural America: Improving Access to Clinical Trials and Quality of Oncologic Care
Discusses the importance of rural populations accessing oncologic clinical trials to decrease cancer morbidity and mortality rates in rural areas. Provides rural versus urban patient data on distance from trial sites as well as prevalence of chronic disease. Suggests strategies and policies to improve access to clinical trials.
Author(s): Joseph M. Unger, Barbara L. McAneny, Raymond U. Osarogiagbon
Citation: CA: A Cancer Journal for Clinicians, 75(4), 341-361
Date: 07/2025
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Lifespan Exposures to Rural-Urban Conditions and Later-Life Cognitive Function
Examines associations between rural or urban residence during childhood and adulthood and cognitive outcomes, including mild cognitive impairment and dementia, among older adults, utilizing 2016 Harmonized Cognitive Assessment Protocol (HCAP) data of 3496 individuals aged 65 years or older.
Author(s): Lingzhi Chu, Yingyan Wu, Heidi Karjalainen, Olivia E Atherton
Citation: Alzheimer's & Dementia, 21(6), e70267
Date: 06/2025
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Development of Chronic Pain and High-Impact Chronic Pain Across the US Rural–Urban Continuum, 2019–2020
Examines the prevalence of chronic pain across large central metro, large fringe metro, medium and small metro, and nonmetropolitan locations in the United States. Utilizes 2019–2020 National Health Interview Survey Longitudinal Cohort (NHIS-LC) data to analyze the severity of pain by demographic variables, region, and rural versus urban location.
Author(s): Feinuo Sun, Yulin Yang, Richard L. Nahin
Citation: Journal of Rural Health, 41(2)
Date: 05/2025
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Rural-Urban Disparities in Hospitalisation for Myocardial Infarction in Systemic Lupus Erythematosus in the USA
Examines rural-urban disparities in hospitalization for myocardial infarction among people with systemic lupus erythematosus (SLE), utilizing 2016-2019 National Inpatient Sample data. Analyzes demographic factors, including sex and geographic region, associated with increased risk of hospitalization.
Author(s): Jasvinder A. Singh, Sumanth Chandrupatla
Citation: Lupus Science & Medicine, 12, e001516
Date: 04/2025
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Uranium Exposure, Hypertension, and Blood Pressure in the Strong Heart Family Study
Examines the correlation between uranium exposure and health conditions such as hypertension and blood pressure changes in rural, tribal communities. Analyzes health status and uranium levels of 1,453 participants in the Strong Heart Family Study. Discusses rock and soil health, groundwater, and surface water contamination as factors in uranium exposure.
Author(s): Kevin P. Patterson, Abigail Onderwyzer Gold, Miranda J. Spratlen, et al.
Citation: Preventing Chronic Disease, 22
Date: 04/2025
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Are HHC Scores a Reliable Health Status Indicator Across Rural and Urban Areas?
Examines differences in Centers for Medicare & Medicaid Services Hierarchical Condition Category (HCC) risk scores between rural and urban Medicare Fee-for-Service (FFS) beneficiaries and analyzes which factors drive observed differences. Features statistics with breakdowns by urban, large rural, small rural, and isolated rural areas for 4 chronic conditions in 2019-2020.
Author(s): Craig D. Holden, Alana Knudson, Marilyn Klug, Samantha Augenbraun, Shena Popat
Date: 04/2025
Sponsoring organization: ETSU/NORC Rural Health Research Center
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Last Updated: 9/29/2025